Patents
US 12747459 B2: System and method for increased alcohol tolerance and production in yeast
- Granted
- 2026-09-29
- Filed
- 2020-09-25 application 17763773
- Type
- Utility · 5 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
A method for producing metabolites that are heavy alcohols, and particularly branched-chain alcohols is provided, involving contacting a suitable substrate with recombinant microorganisms. The microorganisms contain at least one deletion, disruptions, or mutations from the GLN gene family, VPS gene family, GNP gene family, AVT gene family, GCN gene family, or YDR391C, and combinations thereof, and overproduce the heavy alcohol as compared to a wild-type yeast strain.
Source: PTBLXML, file of 2026-09-29 (ipgb20260929.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| THE TRUSTEES OF PRINCETON UNIVERSITY 641 patents | US company or organization | Princeton, NJ | Princeton University College or university FUZZY medium confidence: same name (governing-board words and legal endings aside) and state | PTBLXML, file of 2026-09-29 |
| WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH 176 patents | US company or organization | Cambridge, MA | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH Nonprofit EXACT high confidence: identical full name and state | PTBLXML, file of 2026-09-29 |
| MASSACHUSETTS INSTITUTE OF TECHNOLOGY 5,106 patents | US company or organization | Cambridge, MA | Massachusetts Institute of Technology College or university EXACT high confidence: identical full name and state MASSACHUSETTS INSTITUTE OF TECHNOLOGY Nonprofit EXACT high confidence: identical full name and state | PTBLXML, file of 2026-09-29 |
| KYOTO UNIVERSITY 774 patents | Foreign company or organization | Kyoto, JP | PTBLXML, file of 2026-09-29 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| José L. Avalos | Princeton, NJ | 7 | PTBLXML, file of 2026-09-29 | |
| Sarah K. Hammer | Philadelphia, PA | PTBLXML, file of 2026-09-29 | ||
| Kouichi Kuroda | Kyoto, JP | PTBLXML, file of 2026-09-29 | ||
| Gerald R. Fink | Cambridge, MA | 8 | PTBLXML, file of 2026-09-29 | |
| Gregory Stephanopoulos | Winchester, MA | 41 | PTBLXML, file of 2026-09-29 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C12P | Fermentation or enzyme-using processes to synthesise a desired chemical compound or composition or to separate optical isomers from a racemic mixture | C12P7/04 | PTBLXML, file of 2026-09-29 |
| C12N | Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media | C12N1/185 | PTBLXML, file of 2026-09-29 |
| C12R | Indexing scheme associated with subclasses c12c - c12q, relating to microorganisms | C12R2001/865 | PTBLXML, file of 2026-09-29 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
No recorded assignments or security interests on file for this patent.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.