Patents
US 12747432 B2: Modulating human Cas9-specific host immune response
- Granted
- 2026-09-29
- Filed
- 2024-07-19 application 18778083
- Type
- Utility · 3 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Provided herein are methods and compositions for reducing an undesirable T cell immune response in human patients prior to and/or during gene therapy using CRISPR/Cas9-based genetic modulation.
Source: PTBLXML, file of 2026-09-29 (ipgb20260929.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 1,571 patents | US company or organization | Scottsdale, AZ | PTBLXML, file of 2026-09-29 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Radwa Ewaisha | Tempe, AZ | 3 | PTBLXML, file of 2026-09-29 | |
| Samira Kiani | Scottsdale, AZ | 9 | PTBLXML, file of 2026-09-29 | |
| Shayesteh Roshdi Ferdosi | Tempe, AZ | 3 | PTBLXML, file of 2026-09-29 | |
| Karen Anderson | Scottsdale, AZ | PTBLXML, file of 2026-09-29 | ||
| Farzaneh Moghadam | Tempe, AZ | 5 | PTBLXML, file of 2026-09-29 | |
| Sri Krishna | Tempe, AZ | 5 | PTBLXML, file of 2026-09-29 | |
| Mo Reza Ebrahimkhani | Scottsdale, AZ | 9 | PTBLXML, file of 2026-09-29 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C12N | Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media | C12N9/22 | PTBLXML, file of 2026-09-29 |
| G01N | Investigating or analysing materials by determining their chemical or physical properties | G01N33/573 | PTBLXML, file of 2026-09-29 |
| A61K | Preparations for medical, dental or toiletry purposes | A61K48/00 | PTBLXML, file of 2026-09-29 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
No recorded assignments or security interests on file for this patent.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.