Patents
US 12741964 B2: Macrocyclic complexes of alpha-emitting radionuclides and their use in targeted radiotherapy of cancer
- Granted
- 2026-09-22
- Filed
- 2022-02-23 application 17678793
- Type
- Utility · 13 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The present technology provides compounds as well as compositions including such compounds useful in targeted radiotherapy of cancer and/or mammalian tissue overexpressing prostate specific membrane antigen (“PSMA”) where the compounds are represented by the following: or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable salt thereof, wherein M1 is independently at each occurrence an alpha-emitting radionuclide. Equivalents of such compounds are also disclosed.
Source: PTBLXML, file of 2026-09-22 (ipgb20260922.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| Cornell University 1,393 patents | US company or organization | Ithaca, NY | CORNELL UNIVERSITY State business registration EXACT high confidence: identical full name and state Cornell University College or university EXACT high confidence: identical full name and state CORNELL UNIVERSITY Nonprofit EXACT high confidence: identical full name and state | PTBLXML, file of 2026-09-22 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| John W. Babich | New York, NY | 49 | PTBLXML, file of 2026-09-22 | |
| Justin Wilson | Ithaca, NY | 18 | PTBLXML, file of 2026-09-22 | |
| Nikki Thiele | Brooktondale, NY | 7 | PTBLXML, file of 2026-09-22 | |
| James Kelly | New York, NY | PTBLXML, file of 2026-09-22 | ||
| Shashikanth Ponnala | Ithaca, NY | 16 | PTBLXML, file of 2026-09-22 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C07D | Heterocyclic compounds | C07D413/14 | PTBLXML, file of 2026-09-22 |
| A61K | Preparations for medical, dental or toiletry purposes | A61K51/0463 | PTBLXML, file of 2026-09-22 |
| C07B | General methods of organic chemistry; apparatus therefor | C07B59/002 | PTBLXML, file of 2026-09-22 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
No recorded assignments or security interests on file for this patent.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.