Patents
US 12741937 B2: Tautomeric ligand enables biomimetic C—H hydroxylation with molecular oxygen
- Granted
- 2026-09-22
- Filed
- 2021-12-09 application 18256680
- Type
- Utility · 9 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Disclosed herein is a process for making a compound of formula (2) by (hetero)aromatic C—H hydroxylation of a compound of formula (1): catalyzed by palladium(II) and a bidentate ligand in the presence of O2. The process is useful for instance, in the late-stage modification of medicinally important heterocycles.
Source: PTBLXML, file of 2026-09-22 (ipgb20260922.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| THE SCRIPPS RESEARCH INSTITUTE 569 patents | US company or organization | La Jolla, CA | The Scripps Research Institute State business registration EXACT high confidence: identical full name and state SCRIPPS RESEARCH INSTITUTE Nonprofit FUZZY medium confidence: same name (governing-board words and legal endings aside) and state | PTBLXML, file of 2026-09-22 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Jin-Quan Yu | San Diego, CA | 14 | Person page FUZZY high confidence | PTBLXML, file of 2026-09-22 |
| Zhen Wang | San Diego, CA | PTBLXML, file of 2026-09-22 | ||
| Zhen Li | San Diego, CA | PTBLXML, file of 2026-09-22 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C07D | Heterocyclic compounds | C07D213/803 | PTBLXML, file of 2026-09-22 |
| C07C | Acyclic or carbocyclic compounds | C07C51/373 | PTBLXML, file of 2026-09-22 |
| C07F | Acyclic, carbocyclic or heterocyclic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur, selenium or tellurium | C07F15/0066 | PTBLXML, file of 2026-09-22 |
| C07K | Peptides | C07K5/06078 | PTBLXML, file of 2026-09-22 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
No recorded assignments or security interests on file for this patent.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.