Patents

US 12740763 B2: Treatment planning and aberration correction algorithms for high intensity focused ultrasound (HIFU) ablation of soft tissue targets

Granted
2026-09-22
Filed
2025-08-08 application 19295387
Type
Utility · 22 claims
Elsewhere
Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗

Abstract

Treatment planning and aberration correction algorithms for high intensity focused ultrasound (Hifu) ablation of soft tissue targets, and associated systems and methods are described. In one embodiment, a method for planning a sonication treatment of a target in a body includes obtaining a 3D anatomical model of the target and a portion of the body that is disposed between an ultrasound transducer and the target, where the ultrasound transducer is a phased array ultrasound transducer comprising a plurality of elements. The method also includes: selecting a position of the ultrasound transducer by applying a transducer positioning algorithm for optimizing a sonication geometry; and simulating an aberrated ultrasound field at the target, where the aberrated ultrasound field is a linear high-intensity focused ultrasound (HIFU) field. The method also includes compensating for phase aberrations of the aberrated ultrasound field by: backpropagating an ultrasound field from a virtual point source at the target, through the portion of the body that is disposed between the ultrasound transducer and the target, toward the ultrasound transducer, where the ultrasound field is spherical at the virtual point; and, based on backpropagating the ultrasound field from the virtual point, determining time delays at the elements of the ultrasound transducer, where the time delays are configured for compensating the phase aberrations of the ultrasound field at the virtual point source.

Source: PTBLXML, file of 2026-09-22 (ipgb20260922.xml).

Assignees

AssigneeTypePlaceAlso on furp.orgSource
UNIVERSITY OF WASHINGTON 1,041 patentsUS company or organizationSeattle, WAUNIVERSITY OF WASHINGTON State business registration EXACT high confidence: identical full name and state
UNIVERSITY OF WASHINGTON Federal lobbying client EXACT high confidence: identical full name and state
UNIVERSITY OF WASHINGTON Nonprofit EXACT high confidence: identical full name and state
PTBLXML, file of 2026-09-22

Inventors

InventorPlacePatentsPerson pageSource
Tatiana D. KhokhlovaSeattle, WA11PTBLXML, file of 2026-09-22
Vera A. KhokhlovaSeattle, WA15PTBLXML, file of 2026-09-22
Pavel RosnitskiySeattle, WA2PTBLXML, file of 2026-09-22
Oleg A. SapozhnikovSeattle, WA22PTBLXML, file of 2026-09-22

CPC categories

SubclassCategoryFirst groupSource
A61BDiagnosis; surgery; identificationA61B8/4494PTBLXML, file of 2026-09-22

Cooperative Patent Classification, as currently assigned (one row per subclass).

Assignments and security interests

No recorded assignments or security interests on file for this patent.

USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.