Patents

US 12735753 B2: CRISPR-based assay for detecting TB in bodily fluids

Granted
2026-09-15
Filed
2021-02-05 application 17797425
Type
Utility · 20 claims
Elsewhere
Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗

Abstract

The present disclosure describes a method for detecting the presence of Mycobacterium tuberculosis in a bodily fluid sample. The method utilizes CRISPR effector proteins along with a guide RNA and a reporter molecule, such that when the guide RNA hybridizes with a target nucleotide fragment, the CRISPR effector protein cleaves the reporter molecule, resulting in a detectable signal.

Source: PTBLXML, file of 2026-09-15 (ipgb20260915.xml).

Assignees

AssigneeTypePlaceAlso on furp.orgSource
The Administrators of the Tulane Educational Fund 124 patentsUS company or organizationNew Orleans, LAThe Administrators of the Tulane Educational Fund State business registration EXACT high confidence: identical full name and state
Tulane University of Louisiana College or university EXACT high confidence: through the nonprofit with the college's EIN (identical full name and state)
THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND Nonprofit EXACT high confidence: identical full name and state
PTBLXML, file of 2026-09-15

Inventors

InventorPlacePatentsPerson pageSource
Tony Ye HuNew Orleans, LAPTBLXML, file of 2026-09-15
Bo NingNew Orleans, LAPTBLXML, file of 2026-09-15
Zhen HuangNew Orleans, LAPTBLXML, file of 2026-09-15

CPC categories

SubclassCategoryFirst groupSource
C12QMeasuring or testing processes involving enzymes, nucleic acids or microorganisms ; compositions or test papers therefor; processes of preparing such compositions; condition-responsive control in microbiological or enzymological processesC12Q1/689PTBLXML, file of 2026-09-15
C12NMicroorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture mediaC12N15/1003PTBLXML, file of 2026-09-15

Cooperative Patent Classification, as currently assigned (one row per subclass).

Assignments and security interests

No recorded assignments or security interests on file for this patent.

USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.