Patents

US 12729194 B2: Compounds for the treatment of human immunodeficiency virus

Granted
2026-09-08
Filed
2020-10-01 application 17765983
Type
Utility · 26 claims
Elsewhere
Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗

Abstract

The present disclosure provides compounds of Formula (I) or pharmaceutically acceptable salts thereof: (I) wherein, R1 to R6 and X are defined herein. Also provided are pharmaceutical compositions comprising these compounds, methods for treating Human Immunodeficiency Virus (HIV-1) in a subject in need thereof using these compounds or pharmaceutical compositions, and methods for stabilizing the state-1 conformation of the HIV-1 envelope glycoproteins using these compounds or pharmaceutical compositions.

Source: PTBLXML, file of 2026-09-08 (ipgb20260908.xml).

Assignees

AssigneeTypePlaceAlso on furp.orgSource
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 1,699 patentsUS company or organizationPhiladelphia, PAUniversity of Pennsylvania College or university FUZZY medium confidence: same name (governing-board words and legal endings aside) and state
TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA Nonprofit FUZZY medium confidence: same name (governing-board words and legal endings aside) and state
PTBLXML, file of 2026-09-08
DANA-FARBER CANCER INSTITUTE 892 patentsUS company or organizationBoston, MADANA-FARBER CANCER INSTITUTE, INC. Federal lobbying client EXACT high confidence: identical full name and state
DANA-FARBER CANCER INSTITUTE Nonprofit FUZZY medium confidence: same name (governing-board words and legal endings aside) and state
PTBLXML, file of 2026-09-08

Inventors

InventorPlacePatentsPerson pageSource
Amos B. Smith, IIIMerion, PA23PTBLXML, file of 2026-09-08
Althea Erica GaffneyAlexandria, VAPTBLXML, file of 2026-09-08
Joseph G. SodroskiMedford, MAPTBLXML, file of 2026-09-08

CPC categories

SubclassCategoryFirst groupSource
C07DHeterocyclic compoundsC07D405/14PTBLXML, file of 2026-09-08
A61KPreparations for medical, dental or toiletry purposesA61K39/00PTBLXML, file of 2026-09-08
A61PSpecific therapeutic activity of chemical compounds or medicinal preparationsA61P31/18PTBLXML, file of 2026-09-08

Cooperative Patent Classification, as currently assigned (one row per subclass).

Assignments and security interests

No recorded assignments or security interests on file for this patent.

USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.