Patents

US 12728161 B2: Use of membrane inhibitors to enhance vaccine development against enveloped viruses

Granted
2026-09-08
Filed
2020-11-06 application 17774632
Type
Utility · 10 claims
Elsewhere
Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗

Abstract

The present application relates to method of vaccinating a subject against infection by an enveloped virus. The method includes providing a compound of the Formula (I) as described herein, and contacting the compound of Formula (I) with an isolated enveloped virus, having a membrane, to inactivate the membrane of the isolated enveloped virus. The subject is then treated with the enveloped virus having an inactivated membrane to vaccinate the subject against the enveloped virus. Further disclosed is an ex vivo vaccine composition including the compound of Formula (I) and an enveloped virus.

Source: PTBLXML, file of 2026-09-08 (ipgb20260908.xml).

Assignees

AssigneeTypePlaceAlso on furp.orgSource
CORNELL UNIVERSITY 1,393 patentsUS company or organizationIthaca, NYCORNELL UNIVERSITY State business registration EXACT high confidence: identical full name and state
Cornell University College or university EXACT high confidence: identical full name and state
CORNELL UNIVERSITY Nonprofit EXACT high confidence: identical full name and state
PTBLXML, file of 2026-09-08

Inventors

InventorPlacePatentsPerson pageSource
Hector Aguilar-CarrenoIthaca, NYPTBLXML, file of 2026-09-08
Isaac MonrealIthaca, NYPTBLXML, file of 2026-09-08
David BuchholzIthaca, NYPTBLXML, file of 2026-09-08

CPC categories

SubclassCategoryFirst groupSource
A61KPreparations for medical, dental or toiletry purposesA61K39/29PTBLXML, file of 2026-09-08
A61PSpecific therapeutic activity of chemical compounds or medicinal preparationsA61P31/14PTBLXML, file of 2026-09-08

Cooperative Patent Classification, as currently assigned (one row per subclass).

Assignments and security interests

No recorded assignments or security interests on file for this patent.

USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.