Patents
US 12728155 B2: Compositions and methods for inducing immune tolerance
- Granted
- 2026-09-08
- Filed
- 2022-01-03 application 17567779
- Type
- Utility · 20 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Several embodiments provided in the present disclosure relate to compositions that carry an antigen to which tolerance is desired, the antigen being coupled, bound, or otherwise joined to a targeting moiety, the targeting moiety configured to direct the composition to the liver of a subject. In several embodiments, the antigen in coupled to the targeting moiety by way of a polymeric linker. In several embodiments, the polymeric linker is configured to liberate the antigen in vivo. Methods of using the compositions to reduce and/or prevent unwanted immune responses against an antigen of interest are also provided.
Source: PTBLXML, file of 2026-09-08 (ipgb20260908.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| The University of Chicago 523 patents | US company or organization | Chicago, IL | University of Chicago College or university FUZZY medium confidence: same name (governing-board words and legal endings aside) and state UNIVERSITY OF CHICAGO Nonprofit FUZZY medium confidence: same name (governing-board words and legal endings aside) and state | PTBLXML, file of 2026-09-08 |
| Anokion SA 6 patents | Foreign company or organization | Ecublens, CH | PTBLXML, file of 2026-09-08 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Jeffrey A. Hubbell | Chicago, IL | 59 | PTBLXML, file of 2026-09-08 | |
| David Scott Wilson | Baltimore, MD | 29 | PTBLXML, file of 2026-09-08 | |
| Kristen Marie Lorentz | Boston, MA | 6 | PTBLXML, file of 2026-09-08 | |
| Stephan Kontos | Boston, MA | 15 | PTBLXML, file of 2026-09-08 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K39/0008 | PTBLXML, file of 2026-09-08 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
No recorded assignments or security interests on file for this patent.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.