Patents
US 12728132 B2: Inhibitors of the peptidyl-prolyl cis/trans isomerase (PIN1), combinations and uses thereof
- Granted
- 2026-09-08
- Filed
- 2022-09-23 application 18694557
- Type
- Utility · 21 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Disclosed are methods of treating diseases or disorders mediated by dysregulated CDK4/6 and/or Pin 1 activity comprising co-administering a therapeutically effective amount of one or more CDK4/6 inhibitors, and a therapeutically effective amount of one or more Pin1 inhibitors, or a pharmaceutically acceptable salt or salts thereof.
Source: PTBLXML, file of 2026-09-08 (ipgb20260908.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| DANA-FARBER CANCER INSTITUTE, INC. 892 patents | US company or organization | Boston, MA | DANA-FARBER CANCER INSTITUTE, INC. Federal lobbying client EXACT high confidence: identical full name and state DANA-FARBER CANCER INSTITUTE Nonprofit FUZZY medium confidence: same name (governing-board words and legal endings aside) and state | PTBLXML, file of 2026-09-08 |
| BETH ISRAEL DEACONESS MEDICAL CENTER, INC. 352 patents | US company or organization | Boston, MA | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. State business registration EXACT high confidence: identical full name and state BETH ISRAEL DEACONESS MEDICAL CENTER INC Nonprofit EXACT high confidence: identical full name and state | PTBLXML, file of 2026-09-08 |
| YEDA RESEARCH AND DEVELOPMENT CO. LTD. 528 patents | Foreign company or organization | Rehovot, IL | PTBLXML, file of 2026-09-08 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Shizhong Ke | Boston, MA | PTBLXML, file of 2026-09-08 | ||
| Gerburg Wulf | Boston, MA | 2 | PTBLXML, file of 2026-09-08 | |
| Xiao Zhen Zhou | Newton, MA | 17 | PTBLXML, file of 2026-09-08 | |
| Nir London | Rehovot, IL | PTBLXML, file of 2026-09-08 | ||
| Wenyi Wei | Boston, MA | 6 | PTBLXML, file of 2026-09-08 | |
| Kun Ping Lu | Newton, MA | 18 | PTBLXML, file of 2026-09-08 | |
| Nathanael S. Gray | Stanford, CA | 178 | PTBLXML, file of 2026-09-08 | |
| Behnam Nabet | Boston, MA | 7 | PTBLXML, file of 2026-09-08 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K31/519 | PTBLXML, file of 2026-09-08 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P35/00 | PTBLXML, file of 2026-09-08 |
| C07K | Peptides | C07K16/2827 | PTBLXML, file of 2026-09-08 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
No recorded assignments or security interests on file for this patent.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.