Patents
US 12723249 B2: AAV production strategy using a cell line expressing an inducible rep gene
- Granted
- 2026-09-01
- Filed
- 2020-10-14 application 17767962
- Type
- Utility · 3 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Aspects of the disclosure relate to manufacturing AAV using a stable cell line that expresses the rep gene by engineering tRNA to suppress a mutation introduced to a rep integrated into the genome of the cell line.
Source: PTBLXML, file of 2026-09-01 (ipgb20260901.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| University of Massachusetts 1,152 patents | US company or organization | Westborough, MA | UNIVERSITY OF MASSACHUSETTS Federal lobbying client EXACT high confidence: identical full name and state | PTBLXML, file of 2026-09-01 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Guangping Gao | Worcester, MA | 111 | PTBLXML, file of 2026-09-01 | |
| Dan Wang | Worcester, MA | 45 | PTBLXML, file of 2026-09-01 | |
| Jote Bulcha | Worcester, MA | PTBLXML, file of 2026-09-01 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C12N | Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media | C12N15/52 | PTBLXML, file of 2026-09-01 |
| C07K | Peptides | C07K14/005 | PTBLXML, file of 2026-09-01 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
No recorded assignments or security interests on file for this patent.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.