Patents

US 12723246 B2: Arc protein extracellular vesicle nucleic acid delivery platform

Granted
2026-09-01
Filed
2018-12-11 application 16770834
Type
Utility · 7 claims
Elsewhere
Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗

Abstract

The present invention is related to the field of therapeutic delivery platforms. Such therapeutic delivery platforms are based upon the formation of proteinacous exovesicles that bind nucleic acid payloads (e.g., mRNA, siRNA, shRNA etc.). These nucleic acid payloads may hind to the proteinacous vesicle either directly or as an adduct of a linker molecule. As one example, the linker molecule may be an arc 3′UTR that is bound to an Arc protein exovesicle.

Source: PTBLXML, file of 2026-09-01 (ipgb20260901.xml).

Assignees

AssigneeTypePlaceAlso on furp.orgSource
UNIVERSITY OF MASSACHUSETTS 1,152 patentsUS company or organizationWestborough, MAUNIVERSITY OF MASSACHUSETTS Federal lobbying client EXACT high confidence: identical full name and statePTBLXML, file of 2026-09-01

Inventors

InventorPlacePatentsPerson pageSource
Vivian BudnikRutland, MAPTBLXML, file of 2026-09-01
James AshleyChicago, ILPTBLXML, file of 2026-09-01
Travis ThomsonWorcester, MAPTBLXML, file of 2026-09-01
Lee FradkinBelmont, CAPTBLXML, file of 2026-09-01

CPC categories

SubclassCategoryFirst groupSource
C12NMicroorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture mediaC12N15/113PTBLXML, file of 2026-09-01
A61KPreparations for medical, dental or toiletry purposesA61K9/127PTBLXML, file of 2026-09-01

Cooperative Patent Classification, as currently assigned (one row per subclass).

Assignments and security interests

No recorded assignments or security interests on file for this patent.

USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.