Patents
US 12721863 B2: Treatment for down syndrome-related accelerated aging
- Granted
- 2026-09-01
- Filed
- 2022-06-08 application 18567972
- Type
- Utility · 24 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
A method of treating a Down syndrome (DS) subject with functional or at risk of decline of organ systems associated with accelerated aging due to over-production of H2S is disclosed. That method contemplates administering a pharmaceutical composition containing a H2S-reducing effective amount of hydrophilic polymer-substituted oxidized carbon nanoparticles (OCNPs) and an optional potentiating amount of lipoic acid or dihydrolipoic acid dissolved or dispersed in a physiologically acceptable diluent to the subject. The pharmaceutical composition can be administered parenterally as a liquid or per os as a solid or liquid.
Source: PTBLXML, file of 2026-09-01 (ipgb20260901.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| The Texas A&M University System 801 patents | US company or organization | College Station, TX | PTBLXML, file of 2026-09-01 | |
| The Trustees of Indiana University 158 patents | US company or organization | Bloomington, IN | PTBLXML, file of 2026-09-01 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Thomas A Kent | Houston, TX | PTBLXML, file of 2026-09-01 | ||
| Paul J. Derry | Houston, TX | PTBLXML, file of 2026-09-01 | ||
| Kenneth R. Olson | Berrien Springs, MI | PTBLXML, file of 2026-09-01 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K31/765 | PTBLXML, file of 2026-09-01 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P43/00 | PTBLXML, file of 2026-09-01 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
No recorded assignments or security interests on file for this patent.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.