Patents

US 12718335 B2: Method of CT denoising employing deep learning of multiple co-registered scans of the same person and group convolutional neural network analyses

Granted
2026-08-25
Filed
2022-04-25 application 18325602
Type
Utility · 9 claims
Elsewhere
Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗

Abstract

Disclosed is a novel CT denoising method using deep learning to boost the image signal-to-noise ratio for improved disease detection in patients with acute ischemic stroke (AIS). This method reduced the original CT image noise significantly better than BM3D, with SNR improvements in GM, WM, and DG by 2.47×, 2.83×, and 2.64× respectively and CNR improvements in DG/WM and GM/WM by 2.30× and 2.16× respectively. Scans denoised by the proposed model are shown to be visually clearer with preserved anatomy. The disclosed deep learning model significantly reduces image noise and improves signal-to-noise and contrast-to-noise ratios in 380 unseen head NCCT cases.

Source: PTBLXML, file of 2026-08-25 (ipgb20260825.xml).

Assignees

AssigneeTypePlaceAlso on furp.orgSource
The Methodist Hospital 51 patentsUS company or organizationHouston, TXTHE METHODIST HOSPITAL State business registration EXACT high confidence: identical full name and state
THE METHODIST HOSPITAL Nonprofit EXACT high confidence: identical full name and state
PTBLXML, file of 2026-08-25

Inventors

InventorPlacePatentsPerson pageSource
Kelvin WongHouston, TXPTBLXML, file of 2026-08-25
Stephen T.C. WongHouston, TX6PTBLXML, file of 2026-08-25
John J. VolpiHouston, TXPTBLXML, file of 2026-08-25

CPC categories

SubclassCategoryFirst groupSource
G06TImage data processing or generation, in generalG06T5/70PTBLXML, file of 2026-08-25

Cooperative Patent Classification, as currently assigned (one row per subclass).

Assignments and security interests

RecordedWhatFromToReel/frameSource
2023-06-06Assignment
Assignment of assignor's interest
WONG, KELVIN signed 2023-06-02
WONG, STEPHEN T.C. signed 2023-06-02
VOLPI, JOHN J. signed 2023-06-05
THE METHODIST HOSPITAL HOUSTON, TX63865/316PASDL, file of 2026-08-13
2023-05-30Assignment
Assignment of assignor's interest
WONG, KELVIN signed 2021-04-27
WONG, STEPHEN T.C. signed 2021-04-27
VOLPI, JOHN J. signed 2021-04-27
THE METHODIST HOSPITAL HOUSTON, TX63797/257PASDL, file of 2026-08-13

Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.

USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.