Patents
US 12709608 B2: 4-amino pyrimidine compounds for the treatment of cancer
- Granted
- 2026-08-18
- Filed
- 2022-11-04 application 18052838
- Type
- Utility · 26 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
This patent document discloses novel compounds as inhibitors of the activity of the histone H3K27 demethylase JMJD3. Also disclosed are the use of the compounds and compositions thereof for the treatment of diseases and conditions mediated by JMJD3, in particular cancer, inflammation and autoimmune diseases.
Source: PTBLXML, file of 2026-08-18 (ipgb20260818.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| University of Rochester 570 patents | US company or organization | Rochester, NY | UNIVERSITY OF ROCHESTER State business registration EXACT high confidence: identical full name and state University of Rochester College or university EXACT high confidence: identical full name and state UNIVERSITY OF ROCHESTER Nonprofit EXACT high confidence: identical full name and state | PTBLXML, file of 2026-08-18 |
| Ann & Robert H. Lurie Children's Hospital of Chicago 20 patents | US company or organization | Chicago, IL | ANN & ROBERT H. LURIE CHILDREN'S HOSPITAL OF CHICAGO Federal lobbying client EXACT high confidence: identical full name and state | PTBLXML, file of 2026-08-18 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Venkatesan Srinivasan | Madison, WI | PTBLXML, file of 2026-08-18 | ||
| Frank H. Ebetino | Rochester, NY | PTBLXML, file of 2026-08-18 | ||
| Rintaro Hashizume | Chicago, IL | PTBLXML, file of 2026-08-18 | ||
| Robert K. Boeckman, Jr. | Glenfield, NY | PTBLXML, file of 2026-08-18 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C07D | Heterocyclic compounds | C07D401/14 | PTBLXML, file of 2026-08-18 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P35/00 | PTBLXML, file of 2026-08-18 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
No recorded assignments or security interests on file for this patent.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.