Patents
US 12708608 B2: Methods of treating schizophrenia and other neuropsychiatric disorders
- Granted
- 2026-08-18
- Filed
- 2019-06-18 application 17254008
- Type
- Utility · 15 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The present disclosure is directed to methods of restoring glial cell K+ uptake in a subject. This method involves selecting a subject having impaired glial cell K+ uptake, and administering, to the selected subject, a RE1-Silencing Transcription factor (REST) inhibitor under conditions effective to restore glial cell K+ uptake. Subjects having impaired glial cell K+ uptake include those at risk of having or having a neuropsychiatric disease or disorder.
Source: PTBLXML, file of 2026-08-18 (ipgb20260818.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| University of Rochester 570 patents | US company or organization | Rochester, NY | UNIVERSITY OF ROCHESTER State business registration EXACT high confidence: identical full name and state University of Rochester College or university EXACT high confidence: identical full name and state UNIVERSITY OF ROCHESTER Nonprofit EXACT high confidence: identical full name and state | PTBLXML, file of 2026-08-18 |
| University of Copenhagen 82 patents | Foreign company or organization | Copenhagen K, DK | PTBLXML, file of 2026-08-18 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Steven A. Goldman | Webster, NY | 31 | PTBLXML, file of 2026-08-18 | |
| Zhengshan Liu | Rochester, NY | PTBLXML, file of 2026-08-18 | ||
| Mikhail Osipovitch | Frederiksberg, DK | 2 | PTBLXML, file of 2026-08-18 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K31/19 | PTBLXML, file of 2026-08-18 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P25/28 | PTBLXML, file of 2026-08-18 |
| C12N | Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media | C12N15/113 | PTBLXML, file of 2026-08-18 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2021-12-30 | Assignment Assignment of assignor's interest | OSIPOVITCH, MIKHAIL signed 2021-09-04 | UNIVERSITY OF COPENHAGEN COPENHAGEN K | 58506/283 | PASDL, file of 2026-08-13 |
| 2021-12-30 | Assignment Assignment of assignor's interest | GOLDMAN, STEVEN A. signed 2021-08-04 LIU, ZHENGSHAN signed 2021-08-04 | UNIVERSITY OF ROCHESTER ROCHESTER, NY | 58506/258 | PASDL, file of 2026-08-13 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.