Patents

US 12698261 B2: Cyano-pyrimidine inhibitors of EGFR/HER2

Granted
2026-08-04
Filed
2021-01-06 application 17758437
Type
Utility · 19 claims
Elsewhere
Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗

Abstract

This disclosure provides compounds of Formula (I): or a pharmaceutically acceptable salt thereof and pharmaceutical compositions comprising compounds of Formula (I) or a pharmaceutically acceptable salt thereof which are inhibitors of EGFR and HER2 useful for the treatment of EGFR/HER2 susceptible disorders such as cancer, including cancer of the lung, colon, breast, and thyroid.

Source: PTBLXML, file of 2026-08-04 (ipgb20260804.xml).

Assignees

AssigneeTypePlaceAlso on furp.orgSource
Dana-Farber Cancer Institute, Inc. 892 patentsUS company or organizationBoston, MADANA-FARBER CANCER INSTITUTE, INC. Federal lobbying client EXACT high confidence: identical full name and state
DANA-FARBER CANCER INSTITUTE Nonprofit FUZZY medium confidence: same name (governing-board words and legal endings aside) and state
PTBLXML, file of 2026-08-04

Inventors

InventorPlacePatentsPerson pageSource
Nathanael S. GrayBoston, MA178PTBLXML, file of 2026-08-04
John M. HatcherBoston, MAPTBLXML, file of 2026-08-04

CPC categories

SubclassCategoryFirst groupSource
C07DHeterocyclic compoundsC07D239/22PTBLXML, file of 2026-08-04
A61KPreparations for medical, dental or toiletry purposesA61K45/06PTBLXML, file of 2026-08-04

Cooperative Patent Classification, as currently assigned (one row per subclass).

Assignments and security interests

No recorded assignments or security interests on file for this patent.

USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.