Patents

US 12697313 B2: Methods of treating anemia using formoterol or a pharmaceutically acceptable salt thereof

Granted
2026-08-04
Filed
2023-11-03 application 19127025
Type
Utility · 20 claims
Elsewhere
Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗

Abstract

The present invention provides methods of treating anemia in a patient in need thereof, comprising administering to the patient in need thereof an effective amount of formoterol or a pharmaceutically acceptable salt thereof (e.g., formoterol fumarate or arformoterol tartrate). The formoterol or a pharmaceutically acceptable salt thereof (e.g., formoterol fumarate or arformoterol tartrate) may be administered conjointly with an erythropoiesis-stimulating agent, optionally wherein the anemia is refractory to the erythropoiesis-stimulating agent. The present invention further provides methods of promoting differentiation of an erythroid progenitor cell toward a mature red blood cell in a patient in need thereof, comprising administering an effective amount of formoterol or a pharmaceutically acceptable salt thereof (e.g., formoterol fumarate or arformoterol tartrate). The formoterol or a pharmaceutically acceptable salt thereof (e.g., formoterol fumarate or arformoterol tartrate) may be administered conjointly with other FDA approved drugs such as luspatercept, lenalidomide, erythropoiesis-stimulating agents (ESAs), including but not limited to epoetin alfa or darbepoetin alfa, and/or a hypomethylating agent, such as azacitidine and/or decitabine.

Source: PTBLXML, file of 2026-08-04 (ipgb20260804.xml).

Assignees

AssigneeTypePlaceAlso on furp.orgSource
Dana-Farber Cancer Institute, Inc. 892 patentsUS company or organizationBoston, MADANA-FARBER CANCER INSTITUTE, INC. Federal lobbying client EXACT high confidence: identical full name and state
DANA-FARBER CANCER INSTITUTE Nonprofit FUZZY medium confidence: same name (governing-board words and legal endings aside) and state
PTBLXML, file of 2026-08-04

Inventors

InventorPlacePatentsPerson pageSource
Laurie H. GlimcherBoston, MA18PTBLXML, file of 2026-08-04
Shrestha GhoshBoston, MAPTBLXML, file of 2026-08-04

CPC categories

SubclassCategoryFirst groupSource
A61KPreparations for medical, dental or toiletry purposesA61K31/167PTBLXML, file of 2026-08-04
A61PSpecific therapeutic activity of chemical compounds or medicinal preparationsA61P7/06PTBLXML, file of 2026-08-04

Cooperative Patent Classification, as currently assigned (one row per subclass).

Assignments and security interests

No recorded assignments or security interests on file for this patent.

USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.