Patents
US 12693255 B2: Analyte sensors and sensing methods for detecting creatinine
- Granted
- 2026-07-28
- Filed
- 2019-09-25 application 16582583
- Type
- Utility · 16 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Creatinine levels may be monitored as a measure of kidney function. Conventionally, blood and/or urine tests are used for this purpose. Analyte sensors capable of monitoring creatinine in vivo may comprise: a sensor tail comprising at least a first working electrode, a creatinine-responsive active area disposed upon a surface of the first working electrode, a first membrane that is permeable to creatinine and overcoats the creatinine-responsive active area, and an oxygen scavenger located upon the sensor tail in proximity to the creatinine-responsive active area. The creatinine-responsive active area comprises a first electron transfer agent, a first polymer, and an enzyme system comprising multiple enzymes, particularly creatinine amidohydrolase, creatine amidinohydrolase, and sarcosine oxidase, that are capable of acting in concert to facilitate detection of creatinine. An oxidase enzyme may serve as the oxygen scavenger, particularly glucose oxidase when detecting creatinine in fluids also containing glucose.
Source: PTBLXML, file of 2026-07-28 (ipgb20260728.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| Abbott Diabetes Care Inc. 1,360 patents | US company or organization | Alameda, CA | PTBLXML, file of 2026-07-28 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Tianmei Ouyang | Fremont, CA | 66 | PTBLXML, file of 2026-07-28 | |
| Benjamin J. Feldman | Berkeley, CA | 226 | PTBLXML, file of 2026-07-28 | |
| Hyun Cho | Berkeley, CA | 56 | PTBLXML, file of 2026-07-28 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| G01N | Investigating or analysing materials by determining their chemical or physical properties | G01N27/3271 | PTBLXML, file of 2026-07-28 |
| A61B | Diagnosis; surgery; identification | A61B5/1451 | PTBLXML, file of 2026-07-28 |
| C12Q | Measuring or testing processes involving enzymes, nucleic acids or microorganisms ; compositions or test papers therefor; processes of preparing such compositions; condition-responsive control in microbiological or enzymological processes | C12Q1/002 | PTBLXML, file of 2026-07-28 |
| C12Y | Enzymes | C12Y101/03004 | PTBLXML, file of 2026-07-28 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2019-11-04 | Assignment Assignment of assignor's interest | OUYANG, TIANMEI signed 2019-10-31 FELDMAN, BENJAMIN J. signed 2019-10-31 CHO, HYUN signed 2019-10-31 | ABBOTT DIABETES CARE INC. ALAMEDA, CA | 50900/723 | PASDL, file of 2026-08-13 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.