Patents
US 12692498 B2: Modified oligonucleotides targeting SNPs
- Granted
- 2026-07-28
- Filed
- 2023-08-09 application 18446929
- Type
- Utility · 12 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Novel oligonucleotides that enhance silencing of the expression of a gene containing a single nucleotide polymorphism (SNP) relative to the expression of the corresponding wild-type gene are provided. Methods of using novel oligonucleotides that enhance silencing of the expression of a gene containing a SNP relative to the expression of the corresponding wild-type gene are provided.
Source: PTBLXML, file of 2026-07-28 (ipgb20260728.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| UNIVERSITY OF MASSACHUSETTS 1,152 patents | US company or organization | Westborough, MA | UNIVERSITY OF MASSACHUSETTS Federal lobbying client EXACT high confidence: identical full name and state | PTBLXML, file of 2026-07-28 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Anastasia Khvorova | Westborough, MA | PTBLXML, file of 2026-07-28 | ||
| Julia Alterman | Worcester, MA | 16 | PTBLXML, file of 2026-07-28 | |
| Faith Conroy | Worcester, MA | 4 | PTBLXML, file of 2026-07-28 | |
| Edith Pfister | Boxborough, MA | 8 | PTBLXML, file of 2026-07-28 | |
| Neil Aronin | Newtonville, MA | 28 | PTBLXML, file of 2026-07-28 | |
| Ken Yamada | Boston, MA | 20 | PTBLXML, file of 2026-07-28 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C12N | Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media | C12N15/113 | PTBLXML, file of 2026-07-28 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2026-06-24 | Assignment Assignment of assignor's interest | KHVOROVA, ANASTASIA signed 2019-11-22 ALTERMAN, JULIA signed 2019-11-21 CONROY, FAITH signed 2019-11-18 PFISTER, EDITH signed 2019-08-23 ARONIN, NEIL signed 2019-08-14 YAMADA, KEN signed 2019-08-21 | UNIVERSITY OF MASSACHUSETTS WESTBOROUGH, MA | 75070/88 | PASDL, file of 2026-08-13 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.