Patents
US 12680075 B2: Immune cells derived from induced pluripotent stem cell
- Granted
- 2026-07-14
- Filed
- 2022-10-27 application 18050290
- Type
- Utility · 10 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Embodiments disclosed here are production methods and compositions of engineered immune cells, such as B or T lymphocytes, from limited lineage myeloid progenitor cells, or from pluripotent stem cells, or from multilineage hematopoietic progenitor cells comprising the addition of various cell differentiation transcription factors and inhibiting epigenetic histone methylations in said cells.
Source: PTBLXML, file of 2026-07-14 (ipgb20260714.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| THE CHILDREN'S MEDICAL CENTER CORPORATION 717 patents | US company or organization | Boston, MA | THE CHILDREN'S MEDICAL CENTER CORPORATION State business registration FUZZY medium confidence: same name (legal endings aside) and state | PTBLXML, file of 2026-07-14 |
| PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2,238 patents | US company or organization | Cambridge, MA | Harvard University College or university EXACT high confidence: through the nonprofit with the college's EIN (identical full name and state) PRESIDENT & FELLOWS OF HARVARD COLLEGE Form D issuer EXACT high confidence: identical full name and state PRESIDENT AND FELLOWS OF HARVARD COLLEGE Federal lobbying client EXACT high confidence: identical full name and state PRESIDENT AND FELLOWS OF HARVARD COLLEGE Nonprofit EXACT high confidence: identical full name and state | PTBLXML, file of 2026-07-14 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Linda Thuy Vo | Pacifica, CA | 2 | PTBLXML, file of 2026-07-14 | |
| George Q. Daley | Weston, MA | 14 | PTBLXML, file of 2026-07-14 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C12N | Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media | C12N5/0636 | PTBLXML, file of 2026-07-14 |
| A01K | Animal husbandry; aviculture; apiculture; pisciculture; fishing; rearing or breeding animals, not otherwise provided for; new breeds of animals | A01K67/0271 | PTBLXML, file of 2026-07-14 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2024-12-19 | Other License | BOSTON CHILDREN'S HOSPITAL signed 2023-02-27 | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT BETHESDA, MD | 69735/887 | PASDL, file of 2026-10-15 |
| 2022-11-17 | Assignment Assignment of assignor's interest | VO, LINDA THUY signed 2020-09-23 | PRESIDENT AND FELLOWS OF HARVARD COLLEGE CAMBRIDGE, MA | 61805/395 | PASDL, file of 2026-10-15 |
| 2022-11-17 | Assignment Assignment of assignor's interest | PRESIDENT AND FELLOWS OF HARVARD COLLEGE signed 2021-04-29 | THE CHILDREN'S MEDICAL CENTER CORPORATION BOSTON, MA | 61805/391 | PASDL, file of 2026-10-15 |
| 2022-11-17 | Assignment Assignment of assignor's interest | HOWARD HUGHES MEDICAL INSTITUTE signed 2017-03-30 | THE CHILDREN'S MEDICAL CENTER CORPORATION BOSTON, MA | 61805/277 | PASDL, file of 2026-10-15 |
| 2022-11-17 | Assignment Assignment of assignor's interest | DALEY, GEORGE signed 2017-03-21 | HOWARD HUGHES MEDICAL INSTITUTE CHEVY CHASE, MD | 61805/213 | PASDL, file of 2026-10-15 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.