Patents
US 12678433 B2: Compounds for treatment of hemolysis-and inflammasome-associated diseases
- Granted
- 2026-07-14
- Filed
- 2021-10-13 application 18248644
- Type
- Utility · 15 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Disclosed herein are methods of treating a complication of a hemolysis and/or an inflammasome activation-associated disease comprising administering to a patient in need thereof quinine, or a derivative or salt thereof, or the combination of quinine and hemin. Also disclosed is a method of reducing alloimmunization in chronically transfused subjects, comprising administering to a patient in need thereof a therapeutically effective dose of quinine.
Source: PTBLXML, file of 2026-07-14 (ipgb20260714.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| New York Blood Center, Inc. 57 patents | US company or organization | Rye, NY | NEW YORK BLOOD CENTER INC Nonprofit EXACT high confidence: identical full name and state | PTBLXML, file of 2026-07-14 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Hui Zhong | New York, NY | PTBLXML, file of 2026-07-14 | ||
| Karina Yazdanbakhsh | New York, NY | PTBLXML, file of 2026-07-14 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K31/49 | PTBLXML, file of 2026-07-14 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P7/06 | PTBLXML, file of 2026-07-14 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2023-06-22 | Assignment Assignment of assignor's interest | ZHONG, HUI signed 2020-10-15 YAZDANBAKHSH, KARINA signed 2020-10-15 | NEW YORK BLOOD CENTER, INC. NEW YORK, NY | 64035/214 | PASDL, file of 2026-10-15 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.