Patents
US 12667736 B2: High-dose-rate brachytherapy with optimal needle placement for prostate cancer
- Granted
- 2026-06-30
- Filed
- 2023-02-17 application 18170784
- Type
- Utility · 18 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
A method for needle position optimization for prostate brachytherapy for use with a radiation delivery device configured to use a plurality of needles inserted into a prostate of a patient includes obtaining imagery of the prostate of the patient, generating a needle pool for prostate brachytherapy treatment of the patient based on the imagery of the prostate of the patient, and determining at a computing device an optimum prostate brachytherapy treatment plan for the patient by iteratively removing needles from the needle pool by forming and computationally solving a convex optimization problem wherein the convex optimization problem uses a quadratic dosimetric penalty function, dwell time regularization by total variation, and block sparsity regularization term.
Source: PTBLXML, file of 2026-06-30 (ipgb20260630.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| University of Iowa Research Foundation 401 patents | US company or organization | Iowa City, IA | UNIVERSITY OF IOWA RESEARCH FOUNDATION Nonprofit EXACT high confidence: identical full name and state | PTBLXML, file of 2026-06-30 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Xiaodong Wu | Iowa City, IA | 50 | PTBLXML, file of 2026-06-30 | |
| Weiyu Xu | Iowa City, IA | PTBLXML, file of 2026-06-30 | ||
| Jirong Yi | Iowa City, IA | PTBLXML, file of 2026-06-30 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61N | Electrotherapy; magnetotherapy; radiation therapy; ultrasound therapy | A61N5/1014 | PTBLXML, file of 2026-06-30 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2026-05-05 | Assignment Assignment of assignor's interest | WU, XIAODONG signed 2026-04-30 XU, WEIYU signed 2026-04-30 YI, JIRONG signed 2026-05-03 | UNIVERSITY OF IOWA RESEARCH FOUNDATION IOWA CITY, IA | 74562/918 | PASDL, file of 2026-10-15 |
| 2024-08-13 | Other License | UNIVERSITY OF IOWA signed 2023-05-01 | NATIONAL INSTITUTES OF HEALTH BETHESDA, MD | 68577/244 | PASDL, file of 2026-10-15 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.