Patents
US 12661390 B2: ADAMTS13 treatment to enhance graft survival
- Granted
- 2026-06-23
- Filed
- 2020-10-02 application 17765728
- Type
- Utility · 18 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The disclosure provides a method for treating and/or preventing graft rejection with A Disintegrin And Metalloproteinase with Thrombospondin type 1 motif, member-13 (ADAMT S13). The disclosure provides a method for increasing ADAMTS13-mediated von Willebrand factor (VWF) cleavage in a subject that received a graft by administering ADAMTS13. The disclosure also provides a method of determining the likelihood that a subject will rejection a graft.
Source: PTBLXML, file of 2026-06-23 (ipgb20260623.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| THE CHILDREN'S MEDICAL CENTER CORPORATION 717 patents | US company or organization | Boston, MA | THE CHILDREN'S MEDICAL CENTER CORPORATION State business registration FUZZY medium confidence: same name (legal endings aside) and state | PTBLXML, file of 2026-06-23 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Denisa D. Wagner | Dover, MA | 10 | PTBLXML, file of 2026-06-23 | |
| Siu Ling Wong | Singapore, SG | 4 | PTBLXML, file of 2026-06-23 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K38/4886 | PTBLXML, file of 2026-06-23 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P37/06 | PTBLXML, file of 2026-06-23 |
| C12Y | Enzymes | C12Y304/24082 | PTBLXML, file of 2026-06-23 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2024-12-18 | Other License | BOSTON CHILDREN'S HOSPITAL signed 2023-09-13 | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT BETHESDA, MD | 69730/898 | PASDL, file of 2026-10-15 |
| 2022-04-07 | Assignment Assignment of assignor's interest | WAGNER, DENISA D. signed 2021-01-05 WONG, SIU LING signed 2020-10-28 | THE CHILDREN'S MEDICAL CENTER CORPORATION BOSTON, MA | 59531/651 | PASDL, file of 2026-10-15 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.