Patents
US 12661381 B2: Methods for the delivery of therapeutic agents to donor organs
- Granted
- 2026-06-23
- Filed
- 2019-10-05 application 16594017
- Type
- Utility · 12 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The present invention relates to methods of administering therapeutic agents to a donor organ prior to transplant comprising circulating the therapeutic agent through the donor organ while maintaining the donor organ under ex vivo perfusion conditions, as well as methods of transplanting organs, biologically modifying a donor organ prior to transplant, and treating organ failure using the methods disclosed herein.
Source: PTBLXML, file of 2026-06-23 (ipgb20260623.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| DUKE UNIVERSITY 1,375 patents | US company or organization | Durham, NC | Duke University College or university EXACT high confidence: identical full name and state DUKE UNIVERSITY Nonprofit EXACT high confidence: identical full name and state | PTBLXML, file of 2026-06-23 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Muath Bishawi | Durham, NC | 5 | PTBLXML, file of 2026-06-23 | |
| Carmelo Milano | Durham, NC | PTBLXML, file of 2026-06-23 | ||
| Dawn Bowles | Durham, NC | PTBLXML, file of 2026-06-23 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K35/761 | PTBLXML, file of 2026-06-23 |
| A01N | Preservation of bodies of humans or animals or plants or parts thereof ; biocides, e.g. as disinfectants, as pesticides or as herbicides ; pest repellants or attractants; plant growth regulators | A01N1/126 | PTBLXML, file of 2026-06-23 |
| C12N | Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media | C12N15/113 | PTBLXML, file of 2026-06-23 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2020-01-10 | Assignment Assignment of assignor's interest | BISHAWI, MUATH signed 2019-12-19 MILANO, CARMELO signed 2019-11-29 BOWLES, DAWN signed 2020-01-07 | DUKE UNIVERSITY DUNHAM, NC | 51484/108 | PASDL, file of 2026-10-15 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.