Patents
US 12655432 B2: Oligonucleotides for SOD1 modulation
- Granted
- 2026-06-16
- Filed
- 2022-11-08 application 17982993
- Type
- Utility · 18 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
This disclosure relates to novel SOD1 targeting sequences. Novel SOD1 targeting oligonucleotides for the treatment of SOD1-related familial amyotrophic lateral sclerosis (ALS).
Source: PTBLXML, file of 2026-06-16 (ipgb20260616.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| UNIVERSITY OF MASSACHUSETTS 1,152 patents | US company or organization | Westborough, MA | UNIVERSITY OF MASSACHUSETTS Federal lobbying client EXACT high confidence: identical full name and state | PTBLXML, file of 2026-06-16 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Anastasia Khvorova | Westborough, MA | PTBLXML, file of 2026-06-16 | ||
| James W. Gilbert | Worcester, MA | 3 | PTBLXML, file of 2026-06-16 | |
| Chantal Ferguson | Worcester, MA | 4 | PTBLXML, file of 2026-06-16 | |
| Robert Brown | Needham, MA | PTBLXML, file of 2026-06-16 | ||
| Alexandra Weiss | Bolton, MA | PTBLXML, file of 2026-06-16 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C12N | Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media | C12N15/1137 | PTBLXML, file of 2026-06-16 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P25/28 | PTBLXML, file of 2026-06-16 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2026-05-08 | Assignment Assignment of assignor's interest | WEISS, ALEXANDRA signed 2021-12-06 | UNIVERSITY OF MASSACHUSETTS WESTBOROUGH, MA | 74601/5 | PASDL, file of 2026-10-15 |
| 2026-05-08 | Assignment Assignment of assignor's interest | KHVOROVA, ANASTASIA signed 2021-11-16 GILBERT, JAMES W. signed 2021-12-01 FERGUSON, CHANTAL signed 2021-11-16 BROWN, ROBERT signed 2021-12-16 | UNIVERSITY OF MASSACHUSETTS WESTBOROUGH, MA | 74600/933 | PASDL, file of 2026-10-15 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.