Patents
US 12655138 B2: Process for making an isoxazoline compound and intermediate thereof
- Granted
- 2026-06-16
- Filed
- 2021-07-22 application 18006277
- Type
- Utility · 19 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The present disclosure provides processes for making enantiomerically pure isoxazoline compounds of formula (1), The present disclosure also provides processes for making enantiomerically pure isoxazoline compounds of formula (1) characterized by improving the enantiomeric purity of 3-methyl-5-[(5S)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4H-isoxazol-3-yl]thiophene-2-carboxylic acid by crystallization.
Source: PTBLXML, file of 2026-06-16 (ipgb20260616.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| Elanco US Inc. 52 patents | US company or organization | Greenfield, IN | PTBLXML, file of 2026-06-16 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Jean Marie Defauw | Greenfield, IN | 9 | PTBLXML, file of 2026-06-16 | |
| Guanmin Wu | Greenfield, IN | 2 | PTBLXML, file of 2026-06-16 | |
| Jingdan Hu | Greenfield, IN | 6 | PTBLXML, file of 2026-06-16 | |
| Jing Chen | Greenfield, IN | 19 | PTBLXML, file of 2026-06-16 | |
| Xin Zhang | Greenfield, IN | 22 | PTBLXML, file of 2026-06-16 | |
| Ping Huang | Greenfield, IN | 4 | PTBLXML, file of 2026-06-16 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C07D | Heterocyclic compounds | C07D413/04 | PTBLXML, file of 2026-06-16 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2024-04-29 | Correction Corrective assignment to correct the assignee from sta pharmaceutical r&d co., ltd. to shanghai sta pharmaceutical r&d co., ltd. previously recorded under reel and frame 067108/0934 previously recorded on reel 67108 frame 934. assignor(s) hereby confirms the assignment. | CHEN, JING signed 2021-09-08 ZHANG, XIN signed 2021-09-08 HUANG, PING signed 2021-09-08 | SHANGHAI STA PHARMACEUTICAL R&D CO., LTD. SHANGHAI | 67248/415 | PASDL, file of 2026-10-15 |
| 2024-04-29 | Correction Corrective assignment to correct theshangai sta pharmaceutical r&d co.,ltd. to shanghai sta pharmaceutical r&d co.,ltd. previously recorded under reel and frame 067108/0956. assignor(s) hereby confirms the assignment. | SHANGHAI STA PHARMACEUTICAL R&D CO., LTD. signed 2021-09-08 | STA PHARMACEUTICAL HONG KONG LIMITED WANCHAI | 67248/15 | PASDL, file of 2026-10-15 |
| 2024-04-15 | Assignment Assignment of assignor's interest | STA PHARMACEUTICAL HONG KONG LIMITED signed 2021-09-18 | ELANCO US INC. GREENFIELD, IN | 67108/959 | PASDL, file of 2026-10-15 |
| 2024-04-15 | Assignment Assignment of assignor's interest | SHANGAI STA PHARMACEUTICAL R&D CO., LTD. signed 2021-09-08 | STA PHARMACEUTICAL HONG KONG LIMITED WANCHAI | 67108/956 | PASDL, file of 2026-10-15 |
| 2024-04-15 | Assignment Assignment of assignor's interest | CHEN, JING signed 2021-09-08 ZHANG, XIN signed 2021-09-08 HUANG, PING signed 2021-09-08 | STA PHARMACEUTICAL R&D CO., LTD. SHANGHAI | 67108/934 | PASDL, file of 2026-10-15 |
| 2024-04-15 | Assignment Assignment of assignor's interest | DEFAUW, JEAN MARIE signed 2021-08-23 HU, JINGDAN signed 2021-08-19 WU, GUANMIN signed 2021-08-19 | ELANCO US INC. GREENFIELD, IN | 67108/926 | PASDL, file of 2026-10-15 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.