Patents
US 12653863 B2: FGF21 compositions for treatment or prevention of neovascularization of the eye and methods therefor
- Granted
- 2026-06-16
- Filed
- 2022-04-22 application 17727120
- Type
- Utility · 12 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The instant disclosure provides methods and compositions related to discovery of a long-acting FGF21 as a therapeutic target for treatment or prevention of neovascular eye diseases or disorders that are characterized by angiogenesis, or of vascular diseases of the eye. Therapeutic and/or prophylactic uses and compositions of long-acting FGF21 are described.
Source: PTBLXML, file of 2026-06-16 (ipgb20260616.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| Children's Medical Center Corporation 717 patents | US company or organization | Boston, MA | THE CHILDREN'S MEDICAL CENTER CORPORATION State business registration FUZZY medium confidence: same name (legal endings aside) and state | PTBLXML, file of 2026-06-16 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Lois Smith | West Newton, MA | 7 | PTBLXML, file of 2026-06-16 | |
| Zhongjie Fu | Brookline, MA | PTBLXML, file of 2026-06-16 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K38/1825 | PTBLXML, file of 2026-06-16 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P27/02 | PTBLXML, file of 2026-06-16 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2024-12-18 | Other License | BOSTON CHILDREN'S HOSPITAL signed 2023-02-27 | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT BETHESDA, MD | 69730/752 | PASDL, file of 2026-10-15 |
| 2023-01-20 | Assignment Assignment of assignor's interest | SMITH, LOIS signed 2020-11-11 FU, ZHONGJIE signed 2020-11-11 | CHILDREN'S MEDICAL CENTER CORPORATION BOSTON, MA | 62436/594 | PASDL, file of 2026-10-15 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.