Patents
US 12644122 B2: Compositions and methods for treating amyotrophic lateral sclerosis
- Granted
- 2026-06-02
- Filed
- 2022-03-31 application 17710418
- Type
- Utility · 8 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The present disclosure features methods and compositions for treating amyotrophic lateral sclerosis (ALS). The disclosed methods comprise administering to a subject having or suspected of having ALS a hematopoietic stem progenitor cell expressing at least one neuroprotective agent. The compositions disclosed comprise hematopoietic stem progenitor cells transduced to express a neuroprotective agent.
Source: PTBLXML, file of 2026-06-02 (ipgb20260602.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| The Children's Medical Center Corporation 717 patents | US company or organization | Boston, MA | THE CHILDREN'S MEDICAL CENTER CORPORATION State business registration FUZZY medium confidence: same name (legal endings aside) and state | PTBLXML, file of 2026-06-02 |
| Dana-Farber Cancer Institute, Inc. 892 patents | US company or organization | Boston, MA | DANA-FARBER CANCER INSTITUTE, INC. Federal lobbying client EXACT high confidence: identical full name and state DANA-FARBER CANCER INSTITUTE Nonprofit FUZZY medium confidence: same name (governing-board words and legal endings aside) and state | PTBLXML, file of 2026-06-02 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Alessandra Biffi | Boston, MA | 10 | PTBLXML, file of 2026-06-02 | |
| Marco Peviani | Boston, MA | 3 | PTBLXML, file of 2026-06-02 | |
| Francisco J. Molina-Estevez | Boston, MA | PTBLXML, file of 2026-06-02 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C12N | Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media | C12N15/1137 | PTBLXML, file of 2026-06-02 |
| A61K | Preparations for medical, dental or toiletry purposes | A61K35/28 | PTBLXML, file of 2026-06-02 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P25/28 | PTBLXML, file of 2026-06-02 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2026-02-26 | Assignment Assignment of assignor's interest | PEVIANI, MARCO signed 2022-03-11 | DANA-FARBER CANCER INSTITUTE, INC. BOSTON, MA | 73911/768 | PASDL, file of 2026-10-15 |
| 2026-02-26 | Assignment Assignment of assignor's interest | MOLINA-ESTEVEZ, FRANCISCO J. signed 2022-04-20 | DANA-FARBER CANCER INSTITUTE, INC. BOSTON, MA | 73911/724 | PASDL, file of 2026-10-15 |
| 2026-02-26 | Assignment Assignment of assignor's interest | BIFFI, ALESSANDRA signed 2022-01-19 | THE CHILDREN'S MEDICAL CENTER CORPORATION BOSTON, MA DANA-FARBER CANCER INSTITUTE, INC. BOSTON, MA | 73911/707 | PASDL, file of 2026-10-15 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.