Patents
US 12642837 B2: Methods of preventing or treating fatty degeneration of skeletal muscle
- Granted
- 2026-06-02
- Filed
- 2020-07-22 application 17628495
- Type
- Utility · 22 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Pharmaceutical compositions comprising a selective TGF-β inhibitor, such as a TGFβRII-Fc, are provided herein to prevent, reverse, reduce the occurrence of and/or treat fatty degeneration of skeletal muscle. Additionally, the selective TGF-β inhibitors may be used to inhibit fibro-adipogenic progenitor cell (FAP) differentiation into adipocytes.
Source: PTBLXML, file of 2026-06-02 (ipgb20260602.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| Board of Trustees of Michigan State University 669 patents | US company or organization | East Lansing, MI | PTBLXML, file of 2026-06-02 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Erik Martinez-Hackert | Okemos, MI | 3 | PTBLXML, file of 2026-06-02 | |
| Monique Floer | Okemos, MI | PTBLXML, file of 2026-06-02 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K38/179 | PTBLXML, file of 2026-06-02 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P21/06 | PTBLXML, file of 2026-06-02 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2022-01-21 | Assignment Assignment of assignor's interest | MARTINEZ-HACKERT, ERIK signed 2019-08-03 FLOER, MONIQUE signed 2019-08-03 | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY EAST LANSING, MI | 58723/102 | PASDL, file of 2026-10-15 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.