Patents
US 12637725 B2: Methods, oligonucleotides, and kits for detection and treatment of coronavirus
- Granted
- 2026-05-26
- Filed
- 2021-03-26 application 17914319
- Type
- Utility · 8 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Methods, kits, and oligonucleotides used in the detection of coronavirus, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), are disclosed. In some aspects, the oligonucleotides are primers or probes used in the described methods or kits. The nucleotide sequence of the oligonucleotide consists of 300 or less, 150 or less, or 40 or less continuous nucleotides from a nucleotide sequence selected from the group consisting of: SEQ ID NO:1, SEQ ID NO:2, SEQ ID NO:3, SEQ ID NO:4, and SEQ ID NO: 5, or is a variant thereof. In some embodiments, the oligonucleotide is modified with an internal spacer or a detectable label. For example, the 5′ terminus is labeled with a fluorophore and the 3′ terminus is complexed to a quencher of fluorescence of said fluorophore. In some embodiments, the nucleotide sequence of the oligonucleotide further comprises a universal tail sequence.
Source: PTBLXML, file of 2026-05-26 (ipgb20260526.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE 123 patents | US company or organization | Phoenix, AZ | Translational Genomics Research Institute State business registration FUZZY medium confidence: same name (legal endings aside) and state TRANSLATIONAL GENOMICS RESEARCH INSTITUTE Federal lobbying client FUZZY medium confidence: same name (legal endings aside) and state TRANSLATIONAL GENOMICS RESEARCH INSTITUTE Nonprofit FUZZY medium confidence: same name (governing-board words and legal endings aside) and state | PTBLXML, file of 2026-05-26 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Puiyee Agnes Chan | Phoenix, AZ | PTBLXML, file of 2026-05-26 | ||
| Nicholas J. Schork | Phoenix, AZ | PTBLXML, file of 2026-05-26 | ||
| Yongwook Choi | Phoenix, AZ | PTBLXML, file of 2026-05-26 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C12Q | Measuring or testing processes involving enzymes, nucleic acids or microorganisms ; compositions or test papers therefor; processes of preparing such compositions; condition-responsive control in microbiological or enzymological processes | C12Q1/701 | PTBLXML, file of 2026-05-26 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2022-10-19 | Assignment Assignment of assignor's interest | CHAN, PUIYEE AGNES signed 2021-07-01 SCHORK, NICHOLAS J. signed 2021-07-01 CHOI, YONGWOOK signed 2021-07-01 | THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE PHOENIX, AZ | 61475/637 | PASDL, file of 2026-10-15 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.