Patents

US 12637695 B2: Compositions and methods for regulating fatty acids

Granted
2026-05-26
Filed
2021-01-29 application 17796585
Type
Utility · 19 claims
Elsewhere
Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗

Abstract

Among the various aspects of the present disclosure relates to methods and compositions useful in convert inflammatory dietary fatty acids (omega 6) to anti-inflammatory fatty acids (omega 3). Specifically, the present disclosure provides methods and compositions for increasing n-3 desaturase expression or activity in a subject. The disclosure provides various compositions for providing increased n-3 desaturase expression or activity including a variety of viral vector and engineered microorganisms. The disclosure provides, in part, methods for reducing local and/or systemic inflammation, improving wound healing, preventing premature cellular senescence, treating or preventing a disease, disorder, or condition related to inflammation or obesity and treating or preventing arthritis.

Source: PTBLXML, file of 2026-05-26 (ipgb20260526.xml).

Assignees

AssigneeTypePlaceAlso on furp.orgSource
Washington University 798 patentsUS company or organizationSt. Louis, MOWashington University in St Louis College or university EXACT high confidence: through the nonprofit with the college's EIN (identical full name and state)
WASHINGTON UNIVERSITY Nonprofit EXACT high confidence: identical full name and state
PTBLXML, file of 2026-05-26
Shriners Hospitals for Children 32 patentsUS company or organizationTampa, FLSHRINERS HOSPITALS FOR CHILDREN Nonprofit EXACT high confidence: identical full name and statePTBLXML, file of 2026-05-26

Inventors

InventorPlacePatentsPerson pageSource
Farshid GuilakSt. Louis, MOPTBLXML, file of 2026-05-26
Chia-Lung WuSt. Louis, MOPTBLXML, file of 2026-05-26
Robert NimsSt. Louis, MOPTBLXML, file of 2026-05-26
Ruhang TangSt. Louis, MOPTBLXML, file of 2026-05-26
Arin OestreichSt. Louis, MOPTBLXML, file of 2026-05-26
Natalia HarasymowiczSt. Louis, MOPTBLXML, file of 2026-05-26

CPC categories

SubclassCategoryFirst groupSource
C12NMicroorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture mediaC12N15/86PTBLXML, file of 2026-05-26
A61KPreparations for medical, dental or toiletry purposesA61K9/0053PTBLXML, file of 2026-05-26
C12YEnzymesC12Y103/01PTBLXML, file of 2026-05-26
A01KAnimal husbandry; aviculture; apiculture; pisciculture; fishing; rearing or breeding animals, not otherwise provided for; new breeds of animalsA01K2267/0362PTBLXML, file of 2026-05-26

Cooperative Patent Classification, as currently assigned (one row per subclass).

Assignments and security interests

RecordedWhatFromToReel/frameSource
2023-03-22Assignment
Assignment of assignor's interest
GUILAK, FARSHID signed 2021-02-20WASHINGTON UNIVERSITY ST. LOUIS, MO
SHRINERS HOSPITALS FOR CHILDREN TAMPA, FL
63060/661PASDL, file of 2026-10-15
2023-03-22Assignment
Assignment of assignor's interest
WU, CHIA-LUNG signed 2022-08-14
NIMS, ROBERT signed 2022-08-16
TANG, RUHANG signed 2022-08-12
OESTREICH, ARIN signed 2022-08-12
HARASYMOWICZ, NATALIA signed 2022-08-13
WASHINGTON UNIVERSITY ST. LOUIS, MO63060/553PASDL, file of 2026-10-15

Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.

USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.