Patents
US 12636304 B2: Metabolically stabilized double stranded mRNA
- Granted
- 2026-05-26
- Filed
- 2021-04-20 application 17235535
- Type
- Utility · 16 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Double stranded mRNA, e.g., produced in vitro, as well as method of making and using the ds mRNA, are provided. For example, the disclosure provides a method of expressing a prophylactic or therapeutic protein in mammalian cells in vivo, that includes introducing a composition comprising ds mRNA that encodes a protein to the mammalian cells in an amount effective to express the protein in vivo.
Source: PTBLXML, file of 2026-05-26 (ipgb20260526.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| University of Iowa Research Foundation 401 patents | US company or organization | Iowa City, IA | UNIVERSITY OF IOWA RESEARCH FOUNDATION Nonprofit EXACT high confidence: identical full name and state | PTBLXML, file of 2026-05-26 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Kevin G. Rice | Iowa City, IA | 3 | PTBLXML, file of 2026-05-26 | |
| Samuel T. Crowley | Iowa City, IA | 2 | PTBLXML, file of 2026-05-26 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K31/713 | PTBLXML, file of 2026-05-26 |
| C07H | Sugars; derivatives thereof; nucleosides; nucleotides; nucleic acids | C07H21/02 | PTBLXML, file of 2026-05-26 |
| C12N | Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media | C12N15/67 | PTBLXML, file of 2026-05-26 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
No recorded assignments or security interests on file for this patent.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.