Patents
US 12629394 B2: Atlas of Choroid Plexus cell types and therapeutic and diagnostic uses thereof
- Granted
- 2026-05-19
- Filed
- 2020-04-29 application 16862506
- Type
- Utility · 7 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
A cell atlas of the Choroid Plexus is provided and includes novel markers for cell types. Novel cell types and methods of quantitating, detecting and isolating the cell types are disclosed. Methods of treatment, including for oxidative stress in the brain are provided, as well as methods for controlling differentiation, maintenance and/or function of the cell types disclosed herein.
Source: PTBLXML, file of 2026-05-19 (ipgb20260519.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| The Broad Institute, Inc. 503 patents | US company or organization | Cambridge, MA | BROAD INSTITUTE INC Nonprofit FUZZY medium confidence: same name (governing-board words and legal endings aside) and state | PTBLXML, file of 2026-05-19 |
| Massachusetts Institute of Technology 5,106 patents | US company or organization | Cambridge, MA | Massachusetts Institute of Technology College or university EXACT high confidence: identical full name and state MASSACHUSETTS INSTITUTE OF TECHNOLOGY Nonprofit EXACT high confidence: identical full name and state | PTBLXML, file of 2026-05-19 |
| The Children's Medical Center Corporation 717 patents | US company or organization | Boston, MA | THE CHILDREN'S MEDICAL CENTER CORPORATION State business registration FUZZY medium confidence: same name (legal endings aside) and state | PTBLXML, file of 2026-05-19 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Aviv Regev | Cambridge, MA | 93 | PTBLXML, file of 2026-05-19 | |
| Rebecca Herbst | Cambridge, MA | PTBLXML, file of 2026-05-19 | ||
| Naomi Habib | Cambridge, MA | 3 | PTBLXML, file of 2026-05-19 | |
| Maria Lehtinen | Boston, MA | PTBLXML, file of 2026-05-19 | ||
| Neil Dani | Boston, MA | PTBLXML, file of 2026-05-19 | ||
| Ahram Jang | Boston, MA | PTBLXML, file of 2026-05-19 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K35/36 | PTBLXML, file of 2026-05-19 |
| C12N | Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media | C12N5/0666 | PTBLXML, file of 2026-05-19 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2023-10-02 | Government interest Confirmatory license | BROAD INSTITUTE, INC. signed 2021-02-09 | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT BETHESDA, MD | 65091/345 | PASDL, file of 2026-10-15 |
| 2021-02-03 | Assignment Assignment of assignor's interest | LEHTINEN, MARIA signed 2021-01-22 | THE CHILDREN'S MEDICAL CENTER CORPORATION BOSTON, MA | 55135/226 | PASDL, file of 2026-10-15 |
| 2021-01-06 | Assignment Assignment of assignor's interest | HABIB, NAOMI signed 2020-11-25 | THE BROAD INSTITUTE, INC. CAMBRIDGE, MA | 54829/29 | PASDL, file of 2026-10-15 |
| 2020-10-21 | Assignment Assignment of assignor's interest | HERBST, REBECCA signed 2020-10-04 | THE BROAD INSTITUTE, INC. CAMBRIDGE, MA | 54125/692 | PASDL, file of 2026-10-15 |
| 2020-09-21 | Assignment Assignment of assignor's interest | REGEV, FOR HERSELF AND AS AGENT FOR HOWARD HUGHES MEDICAL INSTITUTE, AVIV signed 2020-09-07 | THE BROAD INSTITUTE, INC. CAMBRIDGE, MA MASSACHUSETTS INSTITUTE OF TECHNOLOGY CAMBRIDGE, MA | 53827/737 | PASDL, file of 2026-10-15 |
| 2020-09-03 | Assignment Assignment of assignor's interest | REGEV, AVIV signed 2019-07-11 | HOWARD HUGHES MEDICAL INSTITUTE CHEVY CHASE, MD | 53687/245 | PASDL, file of 2026-10-15 |
| 2020-07-14 | Assignment Assignment of assignor's interest | JANG, AHRAM signed 2020-07-07 | THE CHILDREN'S MEDICAL CENTER CORPORATION BOSTON, MA | 53201/514 | PASDL, file of 2026-10-15 |
| 2020-07-14 | Assignment Assignment of assignor's interest | DANI, NEIL signed 2020-07-07 | THE CHILDREN'S MEDICAL CENTER CORPORATION BOSTON, MA | 53201/135 | PASDL, file of 2026-10-15 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.