Patents
US 12622976 B2: Targeting CLPTM1L for treatment and prevention of cancer
- Granted
- 2026-05-12
- Filed
- 2024-10-01 application 18903213
- Type
- Utility · 10 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Provided herein are therapeutic agents having specificity for human CLPTM1L/CRR9 polypeptide, including therapeutic agents comprising one or more CLPTM1L-targeting agents, compositions comprising such therapeutic agents, and methods of using such compositions for treating or preventing a cancer, pre-cancerous lesion, or other disease condition associated with CLPTM1L/CRR9 protein dysfunction (e.g., pathogenic production, modification, or function). In particular, provided herein are fully human monoclonal antibodies against human CLPTM1L/CRR9 protein and methods of using such antibodies for treating or preventing a cancer, pre-cancerous lesion, or other disease condition associated with CLPTM1L/CRR9 protein dysfunction (e.g., pathogenic production, modification, or function).
Source: PTBLXML, file of 2026-05-12 (ipgb20260512.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| The Medical College of Wisconsin, Inc. 153 patents | US company or organization | Milwaukee, WI | THE MEDICAL COLLEGE OF WISCONSIN INC Nonprofit EXACT high confidence: identical full name and state Medical College of Wisconsin College or university FUZZY medium confidence: same name (governing-board words and legal endings aside) and state MEDICAL COLLEGE OF WISCONSIN Federal lobbying client FUZZY medium confidence: same name (legal endings aside) and state | PTBLXML, file of 2026-05-12 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Michael A. James | Big Bend, WI | 26 | PTBLXML, file of 2026-05-12 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K47/6851 | PTBLXML, file of 2026-05-12 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P35/00 | PTBLXML, file of 2026-05-12 |
| C07K | Peptides | C07K16/30 | PTBLXML, file of 2026-05-12 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2024-10-01 | Assignment Assignment of assignor's interest | JAMES, MICHAEL A. signed 2020-03-03 | THE MEDICAL COLLEGE OF WISCONSIN, INC. MILWAUKEE, WI | 68752/99 | PASDL, file of 2026-10-15 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.