Patents
US 12605428 B2: Kinase NEK10 and its use in treating and diagnosing bronchiectasis and other respiratory disorders
- Granted
- 2026-04-21
- Filed
- 2021-01-19 application 17793142
- Type
- Utility · 16 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Aspects of the present disclosure provide compositions comprising NEK10 for example, wild-type NEK10 or a hyperactive NEK10 mutant such as NEK10S684D, and methods of using such for treating a respiratory disorder such as bronchiectasis.
Source: PTBLXML, file of 2026-04-21 (ipgb20260421.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| The General Hospital Corporation 1,995 patents | US company or organization | Boston, MA | PTBLXML, file of 2026-04-21 | |
| Whitehead Institute for Biomedical Research 176 patents | US company or organization | Cambridge, MA | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH Nonprofit EXACT high confidence: identical full name and state | PTBLXML, file of 2026-04-21 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Raghu R. Chivukula | Somerville, MA | PTBLXML, file of 2026-04-21 | ||
| David M. Sabatini | Cambridge, MA | 21 | PTBLXML, file of 2026-04-21 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K38/45 | PTBLXML, file of 2026-04-21 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P11/00 | PTBLXML, file of 2026-04-21 |
| G01N | Investigating or analysing materials by determining their chemical or physical properties | G01N33/573 | PTBLXML, file of 2026-04-21 |
| C12Y | Enzymes | C12Y207/11001 | PTBLXML, file of 2026-04-21 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2022-07-29 | Assignment Assignment of assignor's interest | SABATINI, DAVID M. signed 2022-07-26 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH CAMBRIDGE, MA | 60673/722 | PASDL, file of 2026-10-15 |
| 2022-07-29 | Assignment Assignment of assignor's interest | CHIVUKULA, RAGHU R. signed 2021-01-29 | THE GENERAL HOSPITAL CORPORATION BOSTON, MA WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH CAMBRIDGE, MA | 60666/368 | PASDL, file of 2026-10-15 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.