Patents
US 12605398 B2: CRISPR-based compositions for treating vascular disorders
- Granted
- 2026-04-21
- Filed
- 2020-01-27 application 17425494
- Type
- Utility · 3 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
CRISPR-based compositions and methods of their use to impair or promote angiogenesis in a patient to treat indications including, but not limited to, tumor growth, age-related macular degeneration, and metastasis. Single-guide ribonucleic acids sg-RNA-1 (SEQ ID NO: 2) or sg-RNA-2 (SEQ ID NO: 3) are shown to affect angiogenesis.
Source: PTBLXML, file of 2026-04-21 (ipgb20260421.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| The Administrators of the Tulane Educational Fund 124 patents | US company or organization | New Orleans, LA | The Administrators of the Tulane Educational Fund State business registration EXACT high confidence: identical full name and state Tulane University of Louisiana College or university EXACT high confidence: through the nonprofit with the college's EIN (identical full name and state) THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND Nonprofit EXACT high confidence: identical full name and state | PTBLXML, file of 2026-04-21 |
| NATIONAL INSTITUTES OF HEALTH (NIH), U.S DEPT OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 16 patents | US federal government | Bethesda, MD | PTBLXML, file of 2026-04-21 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Shusheng Wang | New Orleans, LA | 6 | PTBLXML, file of 2026-04-21 | |
| Bo Yu | New Orleans, LA | PTBLXML, file of 2026-04-21 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K31/7105 | PTBLXML, file of 2026-04-21 |
| C12N | Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media | C12N9/22 | PTBLXML, file of 2026-04-21 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2024-01-22 | Government interest Confirmatory license | TULANE UNIVERSITY OF LOUISIANA signed 2023-11-14 | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT BETHESDA, MD | 66360/212 | PASDL, file of 2026-10-15 |
| 2022-11-14 | Assignment Assignment of assignor's interest | WANG, SHUSHENG signed 2022-06-27 YU, BO signed 2022-08-25 | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND NEW ORLEANS, LA | 61755/523 | PASDL, file of 2026-10-15 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.