Patents
US 12594283 B2: Mitochondria-targeted atovagone: a more potent and more effective antitumor, antimicrobial, and antimalarial drug
- Granted
- 2026-04-07
- Filed
- 2020-10-26 application 17770924
- Type
- Utility · 22 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The present invention provides novel mitochondria-targeted Atovaquone compounds (Mito-ATO), a mitochondria-targeted derivative of Atovaquone, and methods of using such compounds. Methods of treating cancer using mito-ATO are also provided. Methods of enhancing an anti-tumor immune response by administering mito-ATO are further provided.
Source: PTBLXML, file of 2026-04-07 (ipgb20260407.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| The Medical College of Wisconsin, Inc. 153 patents | US company or organization | Milwaukee, WI | THE MEDICAL COLLEGE OF WISCONSIN INC Nonprofit EXACT high confidence: identical full name and state Medical College of Wisconsin College or university FUZZY medium confidence: same name (governing-board words and legal endings aside) and state MEDICAL COLLEGE OF WISCONSIN Federal lobbying client FUZZY medium confidence: same name (legal endings aside) and state | PTBLXML, file of 2026-04-07 |
| Aix-Marseille Universite 12 patents | Foreign company or organization | Marseilles, FR | PTBLXML, file of 2026-04-07 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Balaraman Kalyanaraman | Milwaukee, WI | 14 | PTBLXML, file of 2026-04-07 | |
| Gang Cheng | Milwaukee, WI | 150 | PTBLXML, file of 2026-04-07 | |
| Micael Joël Hardy | Nimes, FR | PTBLXML, file of 2026-04-07 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K31/66 | PTBLXML, file of 2026-04-07 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P35/00 | PTBLXML, file of 2026-04-07 |
| C07C | Acyclic or carbocyclic compounds | C07C49/84 | PTBLXML, file of 2026-04-07 |
| C07F | Acyclic, carbocyclic or heterocyclic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur, selenium or tellurium | C07F9/535 | PTBLXML, file of 2026-04-07 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2022-04-25 | Assignment Assignment of assignor's interest | KALYANARAMAN, BALARAMAN signed 2020-10-28 CHENG, GANG signed 2020-10-28 | THE MEDICAL COLLEGE OF WISCONSIN, INC. MILWAUKEE, WI | 59693/477 | PASDL, file of 2026-10-15 |
| 2022-04-25 | Assignment Assignment of assignor's interest | HARDY, MICAEL J. signed 2020-11-11 | AIX-MARSEILLE UNIVERSITE MARSEILLE | 59693/380 | PASDL, file of 2026-10-15 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.