Patents
US 12590953 B2: Methods for screening cereblon modifying compounds
- Granted
- 2026-03-31
- Filed
- 2022-06-28 application 17851936
- Type
- Utility · 19 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
A method of screening a cereblon modifying compound for treating a disease or disorder, comprising: obtaining a sample; determining a first protein level of SALL4; administering the cereblon modifying compound to the sample; determining a second protein level of SALL4; comparing the first level and the second protein level of SALL4 to determine if the cereblon modifying compound induces degradation of SALL4; and selecting the cereblon modifying compound that does not induce degradation of SALL4.
Source: PTBLXML, file of 2026-03-31 (ipgb20260331.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| Celgene Corporation 413 patents | US company or organization | Summit, NJ | PTBLXML, file of 2026-03-31 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Mary Matyskiela | San Diego, CA | 4 | PTBLXML, file of 2026-03-31 | |
| Philip Chamberlain | San Diego, CA | 10 | PTBLXML, file of 2026-03-31 | |
| Suzana Sturlini Couto | La Jolla, CA | 3 | PTBLXML, file of 2026-03-31 | |
| Katherine Stamp | Montclair, NJ | 2 | PTBLXML, file of 2026-03-31 | |
| Philip J. Sherratt | Scotch Plains, NJ | 2 | PTBLXML, file of 2026-03-31 | |
| Gang Lu | San Diego, CA | 75 | PTBLXML, file of 2026-03-31 | |
| Julia Hui | Basking Ridge, NJ | 2 | PTBLXML, file of 2026-03-31 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| G01N | Investigating or analysing materials by determining their chemical or physical properties | G01N33/502 | PTBLXML, file of 2026-03-31 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
No recorded assignments or security interests on file for this patent.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.