Patents
US 12590306 B2: Processes for preparing phosphorodiamidate morpholino oligomers via fast-flow synthesis
- Granted
- 2026-03-31
- Filed
- 2024-06-20 application 18749007
- Type
- Utility · 13 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Provided herein are processes for preparing an oligomer (e.g., a morpholino oligomer). The synthetic processes described herein may be advantageous to scaling up oligomersynthesis while maintaining overall yield and purity of a synthesized oligomer.
Source: PTBLXML, file of 2026-03-31 (ipgb20260331.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| Sarepta Therapeutics, Inc. 126 patents | US company or organization | Cambridge, MA | Sarepta Therapeutics, Inc. Form D issuer EXACT high confidence: identical full name and state SAREPTA THERAPEUTICS, INC. SEC filer EXACT medium confidence: identical full name, one of each nationally | PTBLXML, file of 2026-03-31 |
| Massachusetts Institute of Technology 5,106 patents | US company or organization | Cambridge, MA | Massachusetts Institute of Technology College or university EXACT high confidence: identical full name and state MASSACHUSETTS INSTITUTE OF TECHNOLOGY Nonprofit EXACT high confidence: identical full name and state | PTBLXML, file of 2026-03-31 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Kyle A. Totaro | Cambridge, MA | PTBLXML, file of 2026-03-31 | ||
| Mark D. Simon | Cambridge, MA | PTBLXML, file of 2026-03-31 | ||
| Ming Zhou | Cambridge, MA | 35 | PTBLXML, file of 2026-03-31 | |
| Hong Zong | Cambridge, MA | PTBLXML, file of 2026-03-31 | ||
| Gunnar J. Hanson | Cambridge, MA | 58 | PTBLXML, file of 2026-03-31 | |
| Bradley L. Pentelute | Cambridge, MA | 30 | PTBLXML, file of 2026-03-31 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C12N | Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media | C12N15/113 | PTBLXML, file of 2026-03-31 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
No recorded assignments or security interests on file for this patent.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.