Patents

US 12583820 B2: Broad spectrum antivirals against coronavirus

Granted
2026-03-24
Filed
2021-03-30 application 17907745
Type
Utility · 12 claims
Elsewhere
Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗

Abstract

Compounds exhibiting antiviral activity and/or inhibition of viral replication against viruses, particularly those belonging to the picornavirus-like supercluster, including coronavirus having a formula: (I) where X comprises a cyclic moiety, R2 is a branched or unbranched alkyl, cycloalkyl, aryl, arylalkyl, alkenyl, alkynyl, amino acid side chain, bicyclic or tricyclic side chain, combinations, and substituted forms thereof, and Z is selected from the group consisting of C1-C6 hydroxyalkyl, aldehydes, alpha-ketoamides, and bisulfite salts, and in particular —CH2OH, —CHO, —CH(0H)S03−Na+, and -[0(C=0)Rw]S03−Na+.

Source: PTBLXML, file of 2026-03-24 (ipgb20260324.xml).

Assignees

AssigneeTypePlaceAlso on furp.orgSource
Kansas State University Research Foundation 185 patentsUS company or organizationManhattan, KSKANSAS STATE UNIVERSITY RESEARCH FOUNDATION Nonprofit EXACT high confidence: identical full name and statePTBLXML, file of 2026-03-24
Wichita State University 64 patentsUS company or organizationWichita, KSWichita State University College or university EXACT high confidence: identical full name and statePTBLXML, file of 2026-03-24
University of Iowa Research Foundation 401 patentsUS company or organizationIowa City, IAUNIVERSITY OF IOWA RESEARCH FOUNDATION Nonprofit EXACT high confidence: identical full name and statePTBLXML, file of 2026-03-24

Inventors

InventorPlacePatentsPerson pageSource
Kyeong-Ok ChangManhattan, KS7PTBLXML, file of 2026-03-24
Yunjeong KimManhattan, KS8PTBLXML, file of 2026-03-24
William C. GroutasWichita, KS8PTBLXML, file of 2026-03-24
Stanley PerlmanIowa City, IA2PTBLXML, file of 2026-03-24

CPC categories

SubclassCategoryFirst groupSource
C07DHeterocyclic compoundsC07D207/26PTBLXML, file of 2026-03-24

Cooperative Patent Classification, as currently assigned (one row per subclass).

Assignments and security interests

RecordedWhatFromToReel/frameSource
2026-04-27Government interest
Confirmatory license
KANSAS STATE UNIVERSITY signed 2022-11-16NATIONAL INSTITUTES OF HEALTH BETHESDA, MD75476/464PASDL, file of 2026-08-04

Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.

USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.