Patents

US 12577233 B2: Solid forms of APOL1 inhibitor and methods of using same

Granted
2026-03-17
Filed
2021-06-11 application 18001371
Type
Utility · 28 claims
Elsewhere
Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗

Abstract

The disclosure provides novel solid state forms of Compound I selected from ethanol solvate Form A, ethanol solvate Form B, citric acid cocrystal Form A, and Form B, compositions comprising the same, and methods of making and using the same, including use in treating APOL1 mediated kidney disease. (I).

Source: PTBLXML, file of 2026-03-17 (ipgb20260317.xml).

Assignees

AssigneeTypePlaceAlso on furp.orgSource
Vertex Pharmaceuticals Incorporated 764 patentsUS company or organizationBoston, MAPTBLXML, file of 2026-03-17

Inventors

InventorPlacePatentsPerson pageSource
Kevin James GagnonActon, MAPTBLXML, file of 2026-03-17
Jicong LiCambridge, MA3PTBLXML, file of 2026-03-17
Ales MedekWinchester, MA24PTBLXML, file of 2026-03-17
Jack Raphael MinchomSomerville, MAPTBLXML, file of 2026-03-17
Yi ShiNatick, MAPTBLXML, file of 2026-03-17
Muna ShresthaBelmont, MA11PTBLXML, file of 2026-03-17
Faith WitkosAttleboro, MA4PTBLXML, file of 2026-03-17

CPC categories

SubclassCategoryFirst groupSource
C07DHeterocyclic compoundsC07D403/12PTBLXML, file of 2026-03-17
C07BGeneral methods of organic chemistry; apparatus thereforC07B2200/13PTBLXML, file of 2026-03-17

Cooperative Patent Classification, as currently assigned (one row per subclass).

Assignments and security interests

No recorded assignments or security interests on file for this patent.

USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.