Patents
US 12576147 B2: Recombinant proteins with CD40 activating properties
- Granted
- 2026-03-17
- Filed
- 2020-03-26 application 17598582
- Type
- Utility · 17 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
CD40 activating proteins comprising recombinant proteins with CD40 agonist antibodies or their antigen-binding fragments fused or linked to CD40 ligand are provided. The CD40 activating proteins may further comprise at least one antigen. Uses for the CD40 activating proteins include inducing immune responses directed to delivered antigens such as viral or cancer antigens. Properties of the CD40 activating protein may include the ability to induce proliferation of B cells or secretion of cytokines, such as IL-6, IL-12 and/or IL-15.
Source: PTBLXML, file of 2026-03-17 (ipgb20260317.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) | Foreign company or organization | Paris, FR | PTBLXML, file of 2026-03-17 | |
| Université Paris est Cretéil Val de Marne | Foreign company or organization | Cretéil, FR | PTBLXML, file of 2026-03-17 | |
| Baylor Research Institute 79 patents | US company or organization | Dallas, TX | BAYLOR RESEARCH INSTITUTE State business registration EXACT high confidence: identical full name and state BAYLOR RESEARCH INSTITUTE Nonprofit EXACT high confidence: identical full name and state | PTBLXML, file of 2026-03-17 |
| Assistance Publique-Hôpitaux de Paris (APHP) | Foreign company or organization | Paris, FR | PTBLXML, file of 2026-03-17 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Yves Levy | Paris, FR | 17 | PTBLXML, file of 2026-03-17 | |
| Valentina Ceglia | Dallas, TX | PTBLXML, file of 2026-03-17 | ||
| Sandra Zurawski | Midlotian, TX | 34 | PTBLXML, file of 2026-03-17 | |
| Gerard Zurawski | Midlothian, TX | 43 | Person page FUZZY high confidence | PTBLXML, file of 2026-03-17 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K39/39541 | PTBLXML, file of 2026-03-17 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P31/18 | PTBLXML, file of 2026-03-17 |
| C07K | Peptides | C07K14/70575 | PTBLXML, file of 2026-03-17 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
No recorded assignments or security interests on file for this patent.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.