Patents
US 12564617 B2: Methods for modulating macrophage activity
- Granted
- 2026-03-03
- Filed
- 2021-09-17 application 17478042
- Type
- Utility · 14 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Methods according to certain embodiments include contacting a macrophage with a mannose receptor (CD206) binding agent in a manner sufficient to modulate activity of the macrophage. Methods for converting a phenotype of a macrophage from an M2 phenotype to an M1 phenotype are also provided. Methods for inhibiting growth of a CD206-expressing cell as well as methods for treating a subject for a neoplastic condition (e.g., cancer) or a condition associated with chronic inflammation are described. Immuno-modulating peptides suitable for use in the subject methods are also presented.
Source: PTBLXML, file of 2026-03-03 (ipgb20260303.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| Riptide Bioscience, Inc. 9 patents | US company or organization | Vallejo, CA | PTBLXML, file of 2026-03-03 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Jesse Jaynes | Auburn, AL | PTBLXML, file of 2026-03-03 | ||
| Henry Wilfred Lopez | Napa, CA | 9 | PTBLXML, file of 2026-03-03 | |
| George R. Martin | Rockville, MD | 21 | PTBLXML, file of 2026-03-03 | |
| Clayton Yates | Auburn, AL | 7 | PTBLXML, file of 2026-03-03 | |
| Balasubramanyam Karanam | Auburn, AL | PTBLXML, file of 2026-03-03 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K38/08 | PTBLXML, file of 2026-03-03 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P35/00 | PTBLXML, file of 2026-03-03 |
| C12N | Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media | C12N5/0645 | PTBLXML, file of 2026-03-03 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2025-05-20 | Assignment Assignment of assignor's interest | KARANAM, BALASUBRAMANYAM signed 2025-05-19 | RIPTIDE BIOSCIENCE, INC. VALLEJO, CA | 71173/227 | PASDL, file of 2026-10-15 |
| 2021-09-21 | Assignment Assignment of assignor's interest | JAYNES, JESSE signed 2020-06-09 LOPEZ, HENRY WILFRED signed 2020-04-13 MARTIN, GEORGE R. signed 2020-04-18 YATES, CLAYTON signed 2020-04-20 | RIPTIDE BIOSCIENCE, INC. VALLEJO, CA | 57547/103 | PASDL, file of 2026-10-15 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.