Patents
US 12559734 B2: Reverse transcriptase mutants with increased activity and thermostability
- Granted
- 2026-02-24
- Filed
- 2022-01-18 application 17578275
- Type
- Utility · 14 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The disclosure provides Moloney murine leukemia virus (MMLV) reverse transcriptase (RTase) mutants. The disclosure as provides suitable amino acid positions in MMLV RTase for mutagenesis and methods and kits for using MMLV RTase mutants to synthesize cDNA from RNA templates.
Source: PTBLXML, file of 2026-02-24 (ipgb20260224.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| INTEGRATED DNA TECHNOLOGIES, INC. 103 patents | US company or organization | Coralville, IA | INTEGRATED DNA TECHNOLOGIES, INC. State business registration EXACT high confidence: identical full name and state | PTBLXML, file of 2026-02-24 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Sarah Franz Beaudoin | Iowa City, IA | 5 | PTBLXML, file of 2026-02-24 | |
| Christopher Anthony Vakulskas | North Liberty, IA | 22 | PTBLXML, file of 2026-02-24 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C12N | Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media | C12N9/12 | PTBLXML, file of 2026-02-24 |
| C12Y | Enzymes | C12Y207/07049 | PTBLXML, file of 2026-02-24 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
No recorded assignments or security interests on file for this patent.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.