Patents
US 12533415 B2: Core/shell structure platform for immunotherapy
- Granted
- 2026-01-27
- Filed
- 2022-05-24 application 17751812
- Type
- Utility · 14 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Disclosed are biocompatible core/shell compositions suitable for the delivery of populations of mRNA molecules to mammalian cells. The disclosed core-shell structured multicomponent compositions are optimized for the delivery of mRNAs encoding one or more cancer- or tumor-specific antigens to a population of antigen presenting cells, including, for example, human dendritic cells, macrophages and B cells. Also disclosed are methods for use of these compositions as therapeutic cancer vaccines.
Source: PTBLXML, file of 2026-01-27 (ipgb20260127.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| The Methodist Hospital 51 patents | US company or organization | Houston, TX | THE METHODIST HOSPITAL State business registration EXACT high confidence: identical full name and state THE METHODIST HOSPITAL Nonprofit EXACT high confidence: identical full name and state | PTBLXML, file of 2026-01-27 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Haifa Shen | Bellaire, TX | 6 | PTBLXML, file of 2026-01-27 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K45/06 | PTBLXML, file of 2026-01-27 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P35/00 | PTBLXML, file of 2026-01-27 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
No recorded assignments or security interests on file for this patent.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.