Patents
US 12521354 B2: Nanoparticles for targeted non-surgical spaying and neutering
- Granted
- 2026-01-13
- Filed
- 2022-06-08 application 17835739
- Type
- Utility · 18 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Nanoparticles and formulations for non-surgical sterilization are disclosed herein. The nanoparticles for non-surgical sterilization contains a cage, such as a zeolitic imidazolate framework (“ZIF”), a surface modifying agent, a targeting ligand, and an active agent. The surface modifying agent is attached to the outer surface of the cage and the targeting ligand is exposed to the surrounding environment. The active agent is encapsulated in the cage. The targeting ligand binds to a reproductive hormone or a receptor of a reproductive hormone. The active agents can be a ribosome inactivating protein, an apoptosis inducer, a hormone, a receptor ligand, or a nucleic acid, or a combination thereof, that inactivates the ovaries or testes. Uses for the nanoparticles and formulations incorporating the nanoparticles for sterilizing a subject in need thereof are also disclosed.
Source: PTBLXML, file of 2026-01-13 (ipgb20260113.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| University of Georgia Research Foundation, Inc. 535 patents | US company or organization | Athens, GA | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. State business registration EXACT high confidence: identical full name and state UNIVERSITY OF GEORGIA RESEARCH FOUNDATION INC Nonprofit EXACT high confidence: identical full name and state | PTBLXML, file of 2026-01-13 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Sheba M. J. MohanKumar | Athens, GA | 3 | PTBLXML, file of 2026-01-13 | |
| Puliyur S. MohanKumar | Athens, GA | 3 | PTBLXML, file of 2026-01-13 | |
| Yen-Jun Chuang | Athens, GA | 3 | PTBLXML, file of 2026-01-13 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K9/5123 | PTBLXML, file of 2026-01-13 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P15/16 | PTBLXML, file of 2026-01-13 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
No recorded assignments or security interests on file for this patent.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.