Patents
US 12516087 B2: Methods and compositions comprising therapeutic gamma peptide nucleic acid-based molecules
- Granted
- 2026-01-06
- Filed
- 2023-02-07 application 18165809
- Type
- Utility · 11 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Disclosed are compounds and methods for the treatment of diseases or disorders associated with expression of miR-122. More specifically, γ peptide nucleic acid (γPNA) inhibitors of miR-122 and methods of using the same are disclosed.
Source: PTBLXML, file of 2026-02-13 (ipgb20260106.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| UNIVERSITY OF IOWA RESEARCH FOUNDATION 401 patents | US company or organization | Iowa City, IA | UNIVERSITY OF IOWA RESEARCH FOUNDATION Nonprofit EXACT high confidence: identical full name and state | PTBLXML, file of 2026-02-13 |
| UNIVERSITY OF CONNECTICUT 466 patents | US company or organization | Farmington, CT | THE UNIVERSITY OF CONNECTICUT Nonprofit EXACT high confidence: identical full name and state University of Connecticut College or university FUZZY medium confidence: same name (governing-board words and legal endings aside) and state | PTBLXML, file of 2026-02-13 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Ajit Vikram | Iowa City, IA | PTBLXML, file of 2026-02-13 | ||
| Kaikobad Irani | Iowa City, IA | PTBLXML, file of 2026-02-13 | ||
| Ravinder Reddy Gaddam | Iowa City, IA | PTBLXML, file of 2026-02-13 | ||
| Raman Bahal | Glastonbury, CT | 7 | PTBLXML, file of 2026-02-13 | |
| Karishma Mohan Dhuri | Mansfield Center, CT | PTBLXML, file of 2026-02-13 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C07K | Peptides | C07K14/003 | PTBLXML, file of 2026-02-13 |
| C12N | Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media | C12N15/113 | PTBLXML, file of 2026-02-13 |
| A61K | Preparations for medical, dental or toiletry purposes | A61K38/00 | PTBLXML, file of 2026-02-13 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2024-07-24 | Assignment Assignment of assignor's interest | BAHAL, RAMAN signed 2023-02-03 DHURI, KARISHMA MOHAN signed 2023-02-03 | UNIVERSITY OF CONNECTICUT FARMINGTON, CT | 68069/809 | PASDL, file of 2026-10-15 |
| 2024-07-24 | Assignment Assignment of assignor's interest | VIKRAM, AJIT signed 2022-02-14 IRANI, KAIKOBAD signed 2022-02-14 GADDAM, RAVINDER REDDY signed 2022-02-14 | UNIVERSITY OF IOWA RESEARCH FOUNDATION IOWA CITY, IA | 68069/605 | PASDL, file of 2026-10-15 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.