Patents

US 12515028 B2: Multicompartment macroencapsulation devices

Granted
2026-01-06
Filed
2020-04-02 application 17600672
Type
Utility · 29 claims
Elsewhere
Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗

Abstract

Macroencapsulation devices and their methods of use are disclosed. In one embodiment, a macroencapsulation device may include a first outer membrane, a second outer membrane, and at least one semipermeable membrane disposed there between to form at least a primary compartment configured to house a first population of cells and a secondary compartment in fluid communication with the primary compartment through the first semipermeable membrane. In some embodiments, the flow of material into and out of the compartments of the macroencapsulation device and/or the application of an appropriate pressure differential between the compartments may be used to control the flow of filtrates, ancillary agents, and other materials between the compartments of the device when positioned in vivo.

Source: PTBLXML, file of 2026-02-13 (ipgb20260106.xml).

Assignees

AssigneeTypePlaceAlso on furp.orgSource
Vertex Pharmaceuticals Incorporated 764 patentsUS company or organizationBoston, MAPTBLXML, file of 2026-02-13

Inventors

InventorPlacePatentsPerson pageSource
Christopher ThanosCumberland, RI9PTBLXML, file of 2026-02-13
John MillsWarwick, RI6PTBLXML, file of 2026-02-13
Megan BillingsWarwick, RI6PTBLXML, file of 2026-02-13

CPC categories

SubclassCategoryFirst groupSource
A61MDevices for introducing media into, or onto, the body ; devices for transducing body media or for taking media from the body ; devices for producing or ending sleep or stuporA61M31/002PTBLXML, file of 2026-02-13
A61FFilters implantable into blood vessels; prostheses; devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents; orthopaedic, nursing or contraceptive devices; fomentation; treatment or protection of eyes or ears; bandages, dressings or absorbent pads; first-aid kitsA61F2/022PTBLXML, file of 2026-02-13
A61KPreparations for medical, dental or toiletry purposesA61K9/0024PTBLXML, file of 2026-02-13
B01DSeparationB01D69/02PTBLXML, file of 2026-02-13
C12NMicroorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture mediaC12N5/0676PTBLXML, file of 2026-02-13

Cooperative Patent Classification, as currently assigned (one row per subclass).

Assignments and security interests

RecordedWhatFromToReel/frameSource
2022-07-15Assignment
Assignment of assignor's interest
THANOS, CHRISTOPHER signed 2022-06-13
MILLS, JOHN signed 2022-06-28
BILLINGS, MEGAN signed 2022-06-13
VERTEX PHARMACEUTICALS INCORPORATED BOSTON, MA60515/920PASDL, file of 2026-10-15

Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.

USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.