Patents

US 12508231 B2: Formulations of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid

Granted
2025-12-30
Filed
2021-02-12 application 17174764
Type
Utility · 22 claims
Elsewhere
Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗

Abstract

A pharmaceutical composition comprising Compound 1, (3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid), and at least one excipient selected from: a filler, a disintegrant, a surfactant, a binder, and a lubricant, the composition being suitable for oral administration to a patient in need thereof to treat a CFTR mediated disease such as Cystic Fibrosis. Processes of preparing pharmaceutical compositions comprising Compound 1 are also disclosed.

Source: PVGPATDIS, file of 2026-04-10 (ipg251230.xml).

Assignees

AssigneeTypePlaceAlso on furp.orgSource
Vertex Pharmaceuticals Incorporated 764 patentsUS company or organizationBoston, MAPVGPATDIS, file of 2026-04-10

Inventors

InventorPlacePatentsPerson pageSource
Marinus Jacobus VerwijsFramingham, MA8PVGPATDIS, file of 2026-04-10

CPC categories

SubclassCategoryFirst groupSource
A61KPreparations for medical, dental or toiletry purposesA61K9/28PVGPATDIS, file of 2026-04-10
A61JContainers specially adapted for medical or pharmaceutical purposes; devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms; devices for administering food or medicines orally; baby comforters; devices for receiving spittleA61J3/10PVGPATDIS, file of 2026-04-10

Cooperative Patent Classification, as currently assigned (one row per subclass).

Assignments and security interests

RecordedWhatFromToReel/frameSource
2021-03-03Name change
Change of address
VERTEX PHARMACEUTICALS INCORPORATED signed 2016-01-26VERTEX PHARMACEUTICALS INCORPORATED BOSTON, MA55486/97ECORSEXC, file of 2026-09-25
2021-03-03Assignment
Assignment of assignor's interest
VERWIJS, MARINUS JACOBUS signed 2013-03-12VERTEX PHARMACEUTICALS INCORPORATED CAMBRIDGE, MA55480/141ECORSEXC, file of 2026-09-25

Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.

USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.